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TSPAN32

Official Full Name

tetraspanin 32
Overview

This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Synonyms

TSPAN32; tetraspanin 32; pan hematopoietic expression , PHEMX, TSSC6; tetraspanin-32; ART1; FLJ17158; FLJ97586; MGC22455; Pan hematopoietic expression; PHEMX; PHMX; Tetraspanin; tetraspanin32; TSSC6; Tumor suppressing STF cDNA 6; Tumor suppressing subchromosomal transferable fragment cDNA 6; Tumor suppressing subtransferable candidate 6; tspan-32; protein Phemx; tumor-suppressing STF cDNA 6; pan-hematopoietic expression protein; tumor-suppressing subtransferable candidate 6; tumor-suppressing subchromosomal transferable fragment cDNA 6;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Mouse	TSPAN32-17511M	Recombinant Mouse TSPAN32 Protein	Mammalian Cell	His		Inquiry
Mouse	TSPAN32-9686M	Recombinant Mouse TSPAN32 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	TSPAN32-9686M-B	Recombinant Mouse TSPAN32 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Homo sapiens (Human)	RFL29278HF	Recombinant Full Length Human Tetraspanin-32(Tspan32) Protein, His-Tagged	E.coli expression system	His	Full Length (1-320)	Inquiry
Mus musculus (Mouse)	RFL23895MF	Recombinant Full Length Mouse Tetraspanin-32(Tspan32) Protein, His-Tagged	E.coli expression system	His	Full Length (1-256)	Inquiry

Involved Pathway
Protein Function
Interacting Protein

TSPAN32 involved in several pathways and played different roles in them. We selected most pathways TSPAN32 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TSPAN32 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

TSPAN32 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by TSPAN32 itself. We selected most functions TSPAN32 had, and list some proteins which have the same functions with TSPAN32. You can find most of the proteins on our site.

Function	Related Protein
molecular_function	XKR9;GM6710;TESPA1;TRAM1L1;GPM6B;TMEM22;KNSTRN;CCDC71;GM806

TSPAN32 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSPAN32 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSPAN32.