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TSPAN6

  • Official Full Name

    tetraspanin 6

  • Overview

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene.
  • Synonyms

    TSPAN6; tetraspanin 6; TM4SF6, transmembrane 4 superfamily member 6; tetraspanin-6; T245; TSPAN 6; 6720473L21Rik; A15 homolog; AI316786; DKFZp469J2433; MGC117923; MGC133784; Putative NF kappa B activating protein 321; T245 protein; Tetraspan TM4SF; Tetraspanin TM4 D; Tetraspanin TM4D; Tm4sf; TM4SF6; Transmembrane 4 superfamily member 6; Tspan6 protein; tetraspanin TM4-D; putative NF-kappa-B-activating protein 321; TSPAN-6;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Bos taurus (Bovine)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TSPAN6-705HCL Recombinant Human TSPAN6 293 Cell Lysate HEK293 N/A
Mouse Tspan6-6693M Recombinant Mouse Tspan6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Bos taurus (Bovine) RFL21961BF Recombinant Full Length Bovine Tetraspanin-6(Tspan6) Protein, His-Tagged E.coli expression system His Full Length (1-245)
Homo sapiens (Human) RFL28543HF Recombinant Full Length Human Tetraspanin-6(Tspan6) Protein, His-Tagged E.coli expression system His Full Length (1-245)
Mus musculus (Mouse) RFL29900MF Recombinant Full Length Mouse Tetraspanin-6(Tspan6) Protein, His-Tagged E.coli expression system His Full Length (1-245)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL29414PF Recombinant Full Length Pongo Abelii Tetraspanin-6(Tspan6) Protein, His-Tagged E.coli expression system His Full Length (1-245)
Chicken TSPAN6-4982C Recombinant Chicken TSPAN6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TSPAN6 Related Articles
  • TSPAN6 Related Research Area

TSPAN6 involved in several pathways and played different roles in them. We selected most pathways TSPAN6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TSPAN6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TSPAN6 has several biochemical functions, for example, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TSPAN6 itself. We selected most functions TSPAN6 had, and list some proteins which have the same functions with TSPAN6. You can find most of the proteins on our site.

Function Related Protein
protein bindingGTF2F2;PTPRS;TBCB;KPNA2;SAE1;ZAK;KIR2DL4;SMARCA2;HYAL2
signal transducer activityGNGT2B;TAS2R201.1;MRGPRA7;JUPA;GHRHR2;ITGB3BP;TAAR13D;VMN1R40;IL15RA

TSPAN6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSPAN6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSPAN6.

CHD3; RIF1; NSG2

Gopal, AK; Tarantolo, SR; et al. Phase 1b study of otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR (TM) therapeutic protein, in combination with rituximab and bendamustine in relapsed indolent lymphoma patients. INVESTIGATIONAL NEW DRUGS 32:1213-1225(2014).
Dakshinamoorthy, G; von Gegerfelt, A; et al. Evaluation of a Multivalent Vaccine against Lymphatic Filariasis in Rhesus macaque Model. PLOS ONE 9:-(2014).
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