Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

TTC5

  • Official Full Name

    tetratricopeptide repeat domain 5

  • Overview

    Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats. Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5, suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
  • Synonyms

    TTC5; tetratricopeptide repeat domain 5; tetratricopeptide repeat protein 5; OTTHUMP00000163990; OTTHUMP00000163991; TPR repeat protein 5; Strap;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TTC5-1856HCL Recombinant Human TTC5 cell lysate N/A
Human TTC5-3928H Recombinant Human TTC5 protein, His-tagged E.coli His 1-348 aa
Mouse TTC5-17575M Recombinant Mouse TTC5 Protein Mammalian Cell His
Mouse TTC5-9727M-B Recombinant Mouse TTC5 Protein Pre-coupled Magnetic Beads HEK293
Mouse TTC5-9727M Recombinant Mouse TTC5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TTC5-6344R Recombinant Rat TTC5 Protein Mammalian Cell His
Rat TTC5-6000R Recombinant Rat TTC5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TTC5-6000R-B Recombinant Rat TTC5 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish TTC5-2421Z Recombinant Zebrafish TTC5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TTC5 Related Articles

TTC5 involved in several pathways and played different roles in them. We selected most pathways TTC5 participated on our site, such as p53 pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TTC5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
p53 pathwayNEDD8;PPP1R13L;SMYD2;FBXO11;KAT8;DYRK2;HUWE1;RASSF1;CSNK1G3

TTC5 has several biochemical functions, for example, DNA binding, chromatin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TTC5 itself. We selected most functions TTC5 had, and list some proteins which have the same functions with TTC5. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZNF507;DBN1;SIM2;RYBPA;HIST1H2B7;E2F7;GTF2IRD2;ZFP511;NKX2-1
chromatin bindingPOU1F1;MTA1;PHF21A;CBX1;GPR30;ZFP354B;REST;GABPA;HOXD10
protein bindingCTDSP1;TRIM74;MAP2K1;FOXL2;RPS6;ABCF1;DACT2;LIG3;GABARAPL1

TTC5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TTC5 here. Most of them are supplied by our site. Hope this information will be useful for your research of TTC5.

CAMK2B; CAMK2D; HSF1; EP300

Xiong, Y; Wang, L; et al. Human TTC5, a novel tetratricopeptide repeat domain containing gene, activates p53 and inhibits AP-1 pathway. MOLECULAR BIOLOGY REPORTS 40:6183-6188(2013).
Lynch, JT; Somerville, TDD; et al. TTC5 is required to prevent apoptosis of acute myeloid leukemia stem cells. CELL DEATH & DISEASE 4:-(2013).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All TTC5 Products

Required fields are marked with *

My Review for All TTC5 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends