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TXN

  • Official Full Name

    thioredoxin

  • Overview

    The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    TXN; thioredoxin; TRX; ADF; SASP; TXN delta 3; ATL-derived factor; thioredoxin delta 3; surface-associated sulphydryl protein; TRDX; TRX1; MGC61975; DKFZp686B1993;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rhesus Macaque
  • Yeast
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • Mammalian Cell
  • Mammalian cells
  • C
  • Avi
  • 6His
  • Flag
  • GST
  • His
  • His (Fc)
  • Strep
  • His\Avi
  • Myc
  • DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TXN-98H Active Recombinant Human TXN N/A
Human TXN-4662H Active Recombinant Thioredoxin, His-tagged Human His
Human TXN-2556H Active Recombinant Human TXN protein(Met1-Val105) E. coli N/A Met1-Val105
Human TXN-97H Recombinant Human Thioredoxin E.coli N/A
Human TXN-3496H Recombinant Human TXN, GST-tagged E.coli GST 1-105aa
Human TXN-31509TH Recombinant Human TXN E.coli N/A
Human TXN-2356H Recombinant Human Thioredoxin, His-tagged E.coli His
Human TXN-31511TH Recombinant Human TXN, His-tagged E.coli His
Human TXN-627HCL Recombinant Human TXN 293 Cell Lysate HEK293 N/A
Human TXN-018H Recombinant Human TXN Protein E.coli
Human TXN-2011H Recombinant Human TXN Protein, His-tagged E.coli His Val2-Val105
Human TXN-155H Recombinant Human TXN Protein E. coli
Human TXN-47H Recombinant Human TXN Protein, C-Avi&6His tagged, Biotinylated E.coli C-Avi&6His M1-V105
Human TXN-020H Active Recombinant Human TXN Protein E.coli
Human TXN-2132H Recombinant Human TXN Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human TXN-793HFL Recombinant Full Length Human TXN Protein, C-Flag-tagged Mammalian cells Flag
Human TXN-220H Recombinant Human TXN Protein, His\Avi-tagged E.coli His\Avi
Human TXN-0808H Recombinant Human TXN Protein (M1-V105), His/Strep tagged E.coli His/Strep M1-V105
Human TXN-2585H Active Recombinant Human TXN protein, His-tagged E.coli His Val2-Val105
Human TXN-0809H Recombinant Human TXN Protein (M1-V105), Tag Free E.coli No tag M1-V105
Human TXN-2282H Recombinant Human TXN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TXN-2282H-B Recombinant Human TXN Protein Pre-coupled Magnetic Beads HEK293
Human TXN-6524H Recombinant Human TXN Protein (Val2-Val105), N-His tagged E.coli N-His Val2-Val105
Human TXN-019H Recombinant Human TXN Protein E.coli
Human TXN-004H Recombinant Human TXN (C61S/C72S) Protein E.coli
Rhesus Macaque TXN-5036R Recombinant Rhesus monkey TXN Protein, His-tagged Mammalian Cell His
Rhesus Macaque TXN-4849R Recombinant Rhesus Macaque TXN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TXN-4849R-B Recombinant Rhesus Macaque TXN Protein Pre-coupled Magnetic Beads HEK293
Yeast TRX-263Y Recombinant Yeast Thioredoxin E.coli N/A
Yeast LMA1-98Y Recombinant Yeast LMA1 E.coli N/A
Zebrafish TXN-591Z Recombinant Zebrafish TXN Mammalian Cell His
Chicken TXN-7003C Recombinant Chicken TXN Mammalian Cell His
Chicken TXN-492C Recombinant Chicken TXN Protein, His-tagged E.coli N-His Met1-Val105
TRX-262 Recombinant Thioredoxin E.coli N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TXN Related Articles

TXN involved in several pathways and played different roles in them. We selected most pathways TXN participated on our site, such as Cellular Senescence, Cellular responses to stress, Detoxification of Reactive Oxygen Species, which may be useful for your reference. Also, other proteins which involved in the same pathway with TXN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cellular SenescenceACD;RBB4L;POT1A;AGO1;HIST1H1A;TERF1;ERF;HIST1H1C;TXN
Cellular responses to stressPOT1A;NUPL2;BAG3;UVRAG;TERF1;HIST1H1B;SCMH1;HIST1H1D;CBX4
Detoxification of Reactive Oxygen SpeciesTxn1;PRDX2;TXN;TXNRD2;TXN2;PRDX3
Folic Acid NetworkTXN;SEPW1;FMN1
Gene ExpressionZNF669;CHST13;POU2F1;TP53RK;TSEN54;DCP1B;ZNF480;ZNF729;ZNF23
Generic Transcription PathwayRXRBB;NR2F6B;TBX5;ZNF471;ZNF254;ZNF559;C7orf59;RORAA;NR2E3
Immune SystemTRAF7;CTSE;EDAR;DYNC1I1;DEFA5;PELI3;KLHL21;AMICA1;CYBB
InflammasomesBTR29;BTR22;TXNIPA;BTR02;BTR18;PANX1;Txn1;PANX1A;TXNIP

TXN has several biochemical functions, for example, disulfide oxidoreductase activity, oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, protein disulfide oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TXN itself. We selected most functions TXN had, and list some proteins which have the same functions with TXN. You can find most of the proteins on our site.

Function Related Protein
disulfide oxidoreductase activityGRX2;TXNL1;PDIA3;TXN;COIL;DNAJC10;TMX1;PDIA2
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptorTXNL1;ERO1LB;MSRB1A;DNAJC10;MSRB1B;TXN2;TXN;TXNDC8;ERO1L
protein disulfide oxidoreductase activityTXNL1;TXNRD1;TXN;DNAJC10;TXNRD3;TXN2;ERO1L;SH3BGRL3;PTGESL
peptide disulfide oxidoreductase activityTxn1;TXNDC12;TXN
poly(A) RNA bindingDDX27;DHX9;RPS28;ZC3H10;FASTKD1;UBE2I;NSBP1;RPS16;RTCD1
protein bindingC4orf46;GAK;UHMK1;RHOT1;EMG1;NKX2-5;ZNF263;ELF4;SEC23A

TXN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TXN here. Most of them are supplied by our site. Hope this information will be useful for your research of TXN.

EGFR; COPS5; slrP; MYD88

Singh, P; Feld, RI; et al. Sensitization, pathologic, and imaging findings comparing symptomatic and quiescent failed renal allografts. CLINICAL TRANSPLANTATION 28:1424-1432(2014).
Negroni, L; Taouji, S; et al. Integrative Quantitative Proteomics Unveils Proteostasis Imbalance in Human Hepatocellular Carcinoma Developed on Nonfibrotic Livers. MOLECULAR & CELLULAR PROTEOMICS 13:3473-3483(2014).
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Customer Reviews (3)

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Reviews
10/17/2022

    Their team of experts is readily available to address any concerns or queries I may have regarding the TXN protein.

    10/04/2016

      The TXN protein offered by the manufacturer excels in its quality and is an excellent match for my experimental requirements.

      05/29/2016

        Their team of experts is readily available to address any queries or concerns I may have regarding the TXN protein.

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