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TYRO3

  • Official Full Name

    TYRO3 protein tyrosine kinase

  • Overview

    The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010]
  • Synonyms

    TYRO3; TYRO3 protein tyrosine kinase; BYK; Dtk; RSE; Sky; Tif; tyrosine-protein kinase receptor TYRO3; tyrosine-protein kinase DTK; tyrosine-protein kinase RSE; tyrosine-protein kinase SKY; tyrosine-protein kinase TIF; tyrosine-protein kinase byk;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Mammalian cells
  • Sf21
  • Sf9 Insect Cell
  • C
  • Fc
  • mFc
  • Myc
  • DDK
  • DDK|His
  • Flag
  • GST
  • hFc
  • His
  • His (Fc)
  • Avi
  • human|IgG1|Fc
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TYRO3-1506H Active Recombinant Human TYRO3, GST-tagged Sf9 Insect Cell GST 455 aa-end
Human TYRO3-220H Active Recombinant Human TYRO3(451-end) Protein, N-His-tagged Sf21 His 451-end
Human TYRO3-192H Active Recombinant Human TYRO3 Protein, His-tagged HEK293 His Ala41-Ser428
Human TYRO3-195H Recombinant Human TYRO3 protein, DDK/His-tagged HEK293 DDK/His
Human TYRO3-254H Recombinant Human TYRO3 Protein Tyrosine Kinase, GST-tagged, Active Sf9 Insect Cell GST
Human TYRO3-484H Recombinant Human TYRO3 Protein Tyrosine Kinase Mammalian cells N/A
Human TYRO3-749H Recombinant Human TYRO3 Protein Tyrosine Kinase, GST-His Sf9 Insect Cell GST
Human TYRO3-3892H Recombinant Human TYRO3 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human TYRO3-3510H Recombinant Human TYRO3, GST-tagged E.coli GST 57-393aa
Human TYRO3-196H Recombinant Human TYRO3 protein, Fc-tagged HEK293 human/IgG1/Fc 388
Human TYRO3-612H Recombinant Human TYRO3 Protein, DDK-tagged Sf9 Insect Cell DDK
Human TYRO3-31545TH Recombinant Human TYRO3 N/A
Human TYRO3-615HCL Recombinant Human TYRO3 293 Cell Lysate HEK293 N/A
Human TYRO3-2215H Recombinant Human TYRO3 Protein (Ala31-Ser418), C-Fc tagged Mammalian cells C-Fc Ala31-Ser418
Human TYRO3-2703H Active Recombinant Human TYRO3 protein, hFc&His-tagged HEK293 hFc&His Ala41-Ser428
Human TYRO3-4503H Recombinant Human TYRO3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TYRO3-026H Recombinant Human TYRO3 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human TYRO3-4503H-B Recombinant Human TYRO3 Protein Pre-coupled Magnetic Beads HEK293
Human TYRO3-3840H Recombinant Human TYRO3 protein, His-tagged E.coli His 451-596 aa
Human TYRO3-0781H Recombinant Human TYRO3 protein, Fc-tagged HEK293 Fc Ala41-Ser428
Human TYRO3-4489HFL Recombinant Full Length Human TYRO3 protein, Flag-tagged Mamanlian cells Flag
Human TYRO3-6528H Recombinant Human TYRO3 Protein (Ala41-Gln222), N-His tagged E.coli N-His Ala41-Gln222
Mouse Tyro3-414M Active Recombinant Mouse TYRO3 Protein Tyrosine Kinase 3, His-tagged Mammalian cells His
Mouse TYRO3-17674M Recombinant Mouse TYRO3 Protein Mammalian Cell His
Mouse Tyro3-5753M Recombinant Mouse Tyro3 Protein (Ala31-Ser418), C-mFc tagged Mammalian cells C-mFc Ala31-Ser418
Mouse Tyro3-9799M Recombinant Mouse Tyro3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Tyro3-6758M Recombinant Mouse Tyro3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Tyro3-17M Recombinant Mouse Tyro3 Protein, mFc-tagged HEK293 mFc Ala31-Ser418
Mouse TYRO3-9800M Recombinant Mouse TYRO3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Tyro3-18M Recombinant Mouse Tyro3 Protein, Fc-tagged HEK293 Fc Ala31-Ser418
Mouse Tyro3-9799M-B Recombinant Mouse Tyro3 Protein Pre-coupled Magnetic Beads HEK293
Mouse TYRO3-9800M-B Recombinant Mouse TYRO3 Protein Pre-coupled Magnetic Beads HEK293
Rat TYRO3-6382R Recombinant Rat TYRO3 Protein Mammalian Cell His
Rat TYRO3-6038R-B Recombinant Rat TYRO3 Protein Pre-coupled Magnetic Beads HEK293
Rat TYRO3-6038R Recombinant Rat TYRO3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TYRO3-9000Z Recombinant Zebrafish TYRO3 Mammalian Cell His
Chicken TYRO3-6195C Recombinant Chicken TYRO3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TYRO3 Related Articles

TYRO3 involved in several pathways and played different roles in them. We selected most pathways TYRO3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TYRO3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TYRO3 has several biochemical functions, for example, ATP binding, phosphatidylinositol 3-kinase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TYRO3 itself. We selected most functions TYRO3 had, and list some proteins which have the same functions with TYRO3. You can find most of the proteins on our site.

Function Related Protein
ATP bindingPIK3C2B;DGKB;DYRK1AA;NLRP3;TGFBR1A;TEX14;EPHA2;HARS;PEX6
phosphatidylinositol 3-kinase bindingATP1A1;TYRO3;INSRR;LCK;DAB1;INSR;CALM3;IGF1R;IRS4
protein bindingSFN;ITGA4;CCDC153;THBS1;TAE1;CUL4A;Arid4b;SNRPG;SBDS
protein heterodimerization activityHIST2H4A;CENPA;PKNOX1;CYBB;ZHX3;DDIT3;MEF2A;Defa-rs7;MYF6
protein tyrosine kinase activityZAP70;PTK2BB;TESK1;PTK2B;MAP2K3;BLK;ERBB4;TNK1;FGFR1A
receptor signaling protein tyrosine kinase activityERBB2;LYN;TYRO3;KITB;EGFR;ERBB4A;KIT;EGFRA;ERBB3B
transmembrane receptor protein tyrosine kinase activityROS1;EPHB2B;INSRA;TYRO3;KDRL;DDR1;EPHB4A;EGFR;PDGFRA
virus receptor activityHYAL2;CD4;CR2;F11R;AXL;CLEC4G;ACE2;TNFRSF4;XPR1

TYRO3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TYRO3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TYRO3.

KRTAP5-9; KRTAP10-7; KRTAP10-8; KRTAP10-9; KRT40; MDFI

Nguyen, KQN; Tsou, WI; et al. Overexpression of MERTK Receptor Tyrosine Kinase in Epithelial Cancer Cells Drives Efferocytosis in a Gain-of-Function Capacity. JOURNAL OF BIOLOGICAL CHEMISTRY 289:25737-25749(2014).
Shibata, T; Habiel, DM; et al. Axl Receptor Blockade Ameliorates Pulmonary Pathology Resulting from Primary Viral Infection and Viral Exacerbation of Asthma. JOURNAL OF IMMUNOLOGY 192:3569-3581(2014).
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