TNFSF18
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Official Full Name
tumor necrosis factor (ligand) superfamily, member 18
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Overview
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytok -
Synonyms
TNFSF18; tumor necrosis factor (ligand) superfamily, member 18; Activation inducible TNF related ligand; Activation-inducible TNF-related ligand; AITRL; GITRL; Glucocorticoid induced TNF related ligand; Glucocorticoid induced TNFR related protein ligand; Glucocorticoid-induced TNF-related ligand; hGITRL; MGC138237; TL6; TNF18_HUMAN; Tumor necrosis factor (ligand) superfamily member 18; Tumor necrosis factor ligand superfamily member 18; GITR ligand; OTTMUSP00000033308; glucocorticoid-induced-tumor necrosis factor receptor ligand;
- Recombinant Proteins
- Cell & Tissue Lysates
- GMP Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Rhesus monkey
- Zebrafish
- Baculovirus-Insect cells
- CHO
- E.coli
- HEK293
- HEK293F
- HEK293T
- Human Cells
- Insect Cell
- Mammalian cell
- Mammalian Cell
- Mammalian cells
- Avi|Fc
- C
- His
- Fc
- Flag
- hFc
- HIgG1 Fc
- His (Fc)
- Avi
- His(C
- ter)
- His|S
- human|IgG1|Fc
- mFc
- Myc
- DDK
- N/A
- N
- 6×His
- T7
- Involved Pathway
- Protein Function
- Interacting Protein
- TNFSF18 Related Research Area
- TNFSF18 Related Signal Pathway
TNFSF18 involved in several pathways and played different roles in them. We selected most pathways TNFSF18 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNFSF18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | IL3RA;KITLG;CCL27B;TNFRSF11A;PRLR;ACVR2A;IFNA1;CXCL12B;IFNA21 |
TNFSF18 has several biochemical functions, for example, cytokine activity, receptor binding, tumor necrosis factor receptor superfamily binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNFSF18 itself. We selected most functions TNFSF18 had, and list some proteins which have the same functions with TNFSF18. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | CSF1;TGFB1;Flt3l;HMGB1;GDF9;IFNA3;THPO;IL21;CMTM4 |
| receptor binding | ADM;HSD17B4;NUDT19;GUSB;DVL3;TNFSF18;CADM1;PDGFRB;CRH |
| tumor necrosis factor receptor superfamily binding | TNFSF9;TNFSF11;TNFSF18;TNFSF4;FADD |
TNFSF18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNFSF18 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNFSF18.
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