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UBE2V2

  • Official Full Name

    ubiquitin-conjugating enzyme E2 variant 2

  • Overview

    Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes.
  • Synonyms

    UBE2V2; ubiquitin-conjugating enzyme E2 variant 2; DDVit 1; EDPF 1; MMS2; UEV 2; 1 alpha 25 dihydroxyvitamin D3 inducible; 1 alpha 25-dihydroxyvitamin D3 inducible; DDVIT1; EDAF-1; EDAF1; EDPF-1; EDPF1; Enterocyte differentiation associated factor EDAF 1; Enterocyte differentiation promoting factor; Enterocyte differentiation-associated factor 1; Enterocyte differentiation-promoting factor 1; Methyl methanesulfonate sensitive 2; MMS 2; MMS2 homolog; UB2V2_HUMAN; UBE2V 2; Ubiquitin conjugating enzyme E2 variant 2; Ubiquitin conjugating enzyme E2v2; UEV2; Vitamin D3 inducible protein; Vitamin D3-inducible protein; 1 alpha,25-dihydroxyvitamin D3-inducible; enterocyte differentiation-associated factor EDAF-1; methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of; UEV-2; DDVit-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Strep
  • SUMO
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human UBE2V2-60H Recombinant Human UBE2V2, His-tagged E.coli His
Human UBE2V2-30036TH Recombinant Human UBE2V2, His-tagged E.coli His 145 amino acids
Human UBE2V2-210H Recombinant Human UBE2V2, His-tagged E.coli His
Human UBE2V2-143H Recombinant Human UBE2V2 E.coli N/A
Human UBE2V2-559HCL Recombinant Human UBE2V2 293 Cell Lysate HEK293 N/A
Human UBE2V2-3644H Recombinant Human UBE2V2 protein, His-SUMO-tagged E.coli His-SUMO 2-145aa
Human UBE2V2-0522H Recombinant Human UBE2V2 Protein (A2-N145), His/Strep tagged Insect Cell His/Strep A2-N145
Human UBE2V2-0521H Recombinant Human UBE2V2 Protein (A2-N145), Tag Free Insect Cell No tag A2-N145
Mouse UBE2V2-17736M Recombinant Mouse UBE2V2 Protein Mammalian Cell His
Mouse UBE2V2-9840M Recombinant Mouse UBE2V2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse UBE2V2-9840M-B Recombinant Mouse UBE2V2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque UBE2V2-5069R Recombinant Rhesus monkey UBE2V2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque UBE2V2-4882R Recombinant Rhesus Macaque UBE2V2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque UBE2V2-4882R-B Recombinant Rhesus Macaque UBE2V2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish UBE2V2-12674Z Recombinant Zebrafish UBE2V2 Mammalian Cell His
Chicken UBE2V2-2699C Recombinant Chicken UBE2V2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • UBE2V2 Related Research Area

UBE2V2 involved in several pathways and played different roles in them. We selected most pathways UBE2V2 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2V2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemHBEGF;ARIH2;ATG7;RNF4;CD200;BTLA;KLB;CD300LH;DYNC1I2
Antigen processing: Ubiquitination &ampFBXO27;ASB11;RNF123;KLHL20;DTX3L;LRR1;UBE2F;UBE2E3;HUWE1
Proteasome degradationUBE2J2;RNF144B;RNF6;UBE2L6;MKRN1;RNF4;ASB2;ASB8;SPSB4
Cell CycleCDKN1B;CDK1;HTATIP;CTDNEP1B;DIDO1;TUBG2;AKAP9;TSGA14;LEMD3
Cell Cycle CheckpointsCDKN1B;BABAM1;MCM8;BRCC3;THRSP;RNF168;RAD9A;HTATIP;UIMC1
Class I MHC mediated antigen processing &ampRNF34;ASB4;UBE2J2;CD207;TRIM50;ERAP1;ASB3;RBCK1;ASB13
presentationRNF14;UBE2E3;RNF6;ATG7;TPP2;TRAF7;LRSAM1;RNF138;UBR2
DNA Double Strand Break ResponseUBE2V2;RNF168;BARD1;EYA2;HTATIP;SMARCA5;BAZ1B;TP53BP1;EYA4
DNA Double-Strand Break RepairBABAM1;KIAA0146;PARP2;PPP4R2A;RNF4;HTATIP;PARP1;EYA4;EYA3
DNA RepairCHD1L;CHEK2;CLSPN;KIAA0146;FUZ;THRSP;RHNO1;GPS1;KDM4A

UBE2V2 has several biochemical functions, for example, protein binding, ubiquitin conjugating enzyme activity, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2V2 itself. We selected most functions UBE2V2 had, and list some proteins which have the same functions with UBE2V2. You can find most of the proteins on our site.

Function Related Protein
protein bindingSUSD2;SECISBP2;MGAT5B;SDCBP2;NBN;VPS4B;LSM7;2610109H07Rik;CD14
ubiquitin conjugating enzyme activityUBE2E3;UBE2D4;UBE2A;UBE2D2A;UBE2QL1;CDC34;UBE2D2;UBE2T;UBE2G2
ubiquitin protein ligase activityUBE2O;CCNC;ARIH2;UBE2G1A;UHRF2;RFFL;NEDD4;UBE2V1;RBBP6
ubiquitin protein ligase bindingPPARGC1A;AXIN1;TRIM28;ARRB2;CDKN1A;MAGEA2;VCL;WASH;MDM2

UBE2V2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2V2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2V2.

UBE2N; UBC35; EIF1B; TRAF6; EGFR; RNF144A; USP14; XIAP; MKRN3; SNTA1; RIF1; DZIP3; SIAH1; ZNRF1; MALSU1; IGSF21

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