UCK2
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Official Full Name
uridine-cytidine kinase 2
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Overview
This gene encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively. -
Synonyms
UCK2; uridine-cytidine kinase 2; UMPK, uridine monophosphate kinase; uridine kinase; uridine monophosphokinase 2; cytidine monophosphokinase 2; uridine monophosphate kinase; testis-specific protein TSA903; UK; UMPK; TSA903; DKFZp686M04245;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- T7
- Involved Pathway
- Protein Function
- Interacting Protein
UCK2 involved in several pathways and played different roles in them. We selected most pathways UCK2 participated on our site, such as Pyrimidine metabolism, Drug metabolism - other enzymes, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with UCK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Pyrimidine metabolism | ENTPD8;POLR2K;NME2B.1;DTYMK;NT5C1AA;UCK2B;CAD;DCTPP1;RRM2 |
Drug metabolism - other enzymes | UCK1;UGT2A3;UGT1A4;UGT2A1;UGT1A9;GMPS;NAT1;NAT;UPB1 |
Metabolic pathways | QPRT;GCNT1;TYRP1;AKR1B1L;ALOX5A;CYP3A41B;CCBL2;COX5A;RDH10 |
UCK2 has several biochemical functions, for example, ATP binding, nucleoside kinase activity, uridine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UCK2 itself. We selected most functions UCK2 had, and list some proteins which have the same functions with UCK2. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | ABCB1A;STK31;TAOK1;ACSL1;UBE2A;KIF15;ACSS1;CDK16;DHX8 |
nucleoside kinase activity | UCK1;TK1;UCK2;UCK2A;DCK;UCK2B;DGUOK |
uridine kinase activity | UPRT;UCKL1;UCKL1A;UCK1;UCK2;CMPK1;UCK2B;UCK2A |
UCK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UCK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UCK2.
TSC22D1; NEK6; VCAM1
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, UCK2 protein levels can be quantified in patient samples using techniques such as immunohistochemistry and ELISA for clinical assessment.
Certain genetic mutations in the UCK2 gene have been linked to altered UCK2 protein function, which may impact clinical outcomes in certain diseases.
Some studies have suggested a potential link between UCK2 protein and neurological disorders, although further research is needed to fully understand this association.
UCK2 protein has been implicated in liver diseases, particularly in the context of nucleoside analog metabolism and liver cell function.
UCK2 protein has been associated with drug resistance in cancer cells, particularly in the context of chemotherapy.
Customer Reviews (3)
Write a reviewI highly endorse the utilization of the UCK2 Protein for researchers seeking a superior protein solution that not only meets their experimental needs but also benefits from the exceptional technical support provided by the manufacturer.
Their expertise has proven instrumental in overcoming obstacles and has greatly contributed to the success of my research endeavors.
Their team of experts has been extremely helpful in addressing any concerns or queries I encountered during my experiments.
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