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UNC5C

  • Official Full Name

    unc-5 homolog C (C. elegans)

  • Overview

    This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.
  • Synonyms

    UNC5C; unc-5 homolog C (C. elegans); unc5 (C.elegans homolog) c; netrin receptor UNC5C; UNC5H3; homolog of C. elegans transmembrane receptor Unc5; Protein unc 5 homolog C; Unc 5 homolog 3; Unc 5 homolog C; unc-5 homolog 3; OTTHUMP00000161619; OTTHUMP00000219358; protein unc-5 homolog 3; protein unc-5 homolog C;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human UNC5C-1072H Active Recombinant Human UNC5C Protein, Fc Chimera Mammalian cells Fc
Human UNC5C-3599H Recombinant Human UNC5C, GST-tagged E.coli GST 473-578aa
Human UNC5C-164H-B Recombinant Human UNC5C Protein Pre-coupled Magnetic Beads HEK293
Human UNC5C-674H Recombinant Human UNC5C Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human UNC5C-633H Recombinant Human UNC5C Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human UNC5C-164H Recombinant Human UNC5C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse UNC5C-17849M Recombinant Mouse UNC5C Protein Mammalian Cell His
Mouse UNC5C-9918M Recombinant Mouse UNC5C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse UNC5C-9918M-B Recombinant Mouse UNC5C Protein Pre-coupled Magnetic Beads HEK293
Mouse Unc5c-6839M Recombinant Mouse Unc5c Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat UNC5C-6452R Recombinant Rat UNC5C Protein Mammalian Cell His
Rat UNC5C-6108R Recombinant Rat UNC5C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat UNC5C-6108R-B Recombinant Rat UNC5C Protein Pre-coupled Magnetic Beads HEK293
Zebrafish UNC5C-5796Z Recombinant Zebrafish UNC5C Mammalian Cell His
Chicken UNC5C-6021C Recombinant Chicken UNC5C Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • UNC5C Related Research Area

UNC5C involved in several pathways and played different roles in them. We selected most pathways UNC5C participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with UNC5C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceDOCK1;EFNB1;EFNB3;SLIT1;NFATC4;CD24;EPHB4A;GFRA1;RGMA

UNC5C has several biochemical functions, for example, netrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UNC5C itself. We selected most functions UNC5C had, and list some proteins which have the same functions with UNC5C. You can find most of the proteins on our site.

Function Related Protein
netrin receptor activityUnc5b;UNC5C

UNC5C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UNC5C here. Most of them are supplied by our site. Hope this information will be useful for your research of UNC5C.

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