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UROC1

Official Full Name

urocanase domain containing 1
Overview

This gene encodes an enzyme involved in histidine catabolism, metabolizing urocanic acid to formiminoglutamic acid. The gene product is known to protect the skin from ultra violet rays and is contained in human sweat. Deficiency of this gene product in the liver is an apparent cause of mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms

UROC1; urocanase domain containing 1; urocanate hydratase; FLJ31300; HMFN0320; HUTU_HUMAN; Imidazolonepropionate hydrolase; MGC135007; MGC135008; Urocanase;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	UROC1-484HCL	Recombinant Human UROC1 293 Cell Lysate	HEK293	N/A	Inquiry
Human	UROC1-1595H	Recombinant Human UROC1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	Uroc1-6856M	Recombinant Mouse Uroc1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Zebrafish	UROC1-7183Z	Recombinant Zebrafish UROC1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

UROC1 involved in several pathways and played different roles in them. We selected most pathways UROC1 participated on our site, such as Histidine catabolism, Histidine metabolism, Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with UROC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Histidine catabolism	FTCD;UROC1;AMDHD1
Histidine metabolism	HDC;ALDH9A1B;CNDP1;ALDH9A1;ABP1;AMDHD1;MAOA;MAOB;ALDH2
Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism	DLST;IDO2;AFMID;PCBD1;SLC25A21;AMDHD1;UROC1;FTCD;ACMSD
Metabolic pathways	CYP19A1B;NMNAT1;NDUFS8;ST3GAL6;ALG14;STT3A;PLA2G2F;NMRK2;CMAS
Metabolism	NQO1;LBR;SULT1ST6;PDK2;FA2H;UCP2;KCNS3A;SIN3B;AKR1C4
Metabolism of amino acids and derivatives	BHMT2;ACMSD;NAGS;AHCY;SLC25A15A;OAZ3;SLC6A8;BCKDK;CDO1
histidine degradation	UROC1;AMDHD1

UROC1 has several biochemical functions, for example, urocanate hydratase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UROC1 itself. We selected most functions UROC1 had, and list some proteins which have the same functions with UROC1. You can find most of the proteins on our site.

Function	Related Protein
urocanate hydratase activity

UROC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UROC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UROC1.