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UROS

  • Official Full Name

    uroporphyrinogen III synthase

  • Overview

    The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunthers disease).
  • Synonyms

    UROS; uroporphyrinogen III synthase; uroporphyrinogen-III synthase; congenital erythropoietic porphyria; HEM4_HUMAN; Hydroxymethylbilane hydrolyase [cyclizing]; Hydroxymethylbilane hydrolyase; UROIIIS; Uroporphyrinogen III cosynthetase; Uroporphyrinogen III synthase (congenital erythropoietic porphyria); Uroporphyrinogen-III cosynthase; OTTHUMP00000020709; OTTHUMP00000020710; OTTHUMP00000020712;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human UROS-622H Recombinant Human UROS Protein, His-tagged E.coli His
Human UROS-996H Recombinant Human Uroporphyrinogen III Synthase, His-tagged E.coli His
Human UROS-31080TH Recombinant Human UROS, His-tagged E.coli His
Human UROS-31079TH Recombinant Human UROS, His-tagged E.coli His 265 amino acids
Human UROS-482HCL Recombinant Human UROS 293 Cell Lysate HEK293 N/A
Mouse UROS-17888M Recombinant Mouse UROS Protein Mammalian Cell His
Mouse Uros-6858M Recombinant Mouse Uros Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse UROS-9940M Recombinant Mouse UROS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse UROS-9940M-B Recombinant Mouse UROS Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque UROS-5117R Recombinant Rhesus monkey UROS Protein, His-tagged Mammalian Cell His
Rhesus Macaque UROS-4930R Recombinant Rhesus Macaque UROS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque UROS-4930R-B Recombinant Rhesus Macaque UROS Protein Pre-coupled Magnetic Beads HEK293
Zebrafish UROS-12094Z Recombinant Zebrafish UROS Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

UROS involved in several pathways and played different roles in them. We selected most pathways UROS participated on our site, such as Porphyrin and chlorophyll metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with UROS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Porphyrin and chlorophyll metabolismCOX15;HEPH;BLVRB;UGT5G1;UGT1A6B;BLVRA;HMBSA;UGT1A7C;COX10
Metabolic pathwaysGSS;ST3GAL2;CYP26B1;MGAT2;NT5M;ADSSL1;AKR1B10;GLDC;ATP6V1A

UROS has several biochemical functions, for example, cofactor binding, uroporphyrinogen-III synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UROS itself. We selected most functions UROS had, and list some proteins which have the same functions with UROS. You can find most of the proteins on our site.

Function Related Protein
cofactor bindingPHYH;HACL1;DAO;TKT;DDO;UROS;WWOX;ACLY;LMO2
uroporphyrinogen-III synthase activity

UROS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UROS here. Most of them are supplied by our site. Hope this information will be useful for your research of UROS.

PA; UBQLN4

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