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VIPR2

  • Official Full Name

    vasoactive intestinal peptide receptor 2

  • Overview

    Vasoactive intestinal peptide (VIP; MIM 192320) and pituitary adenylate cyclase activating polypeptide (PACAP; MIM 102980) are homologous peptides that function as neurotransmitters and neuroendocrine hormones. While the receptors for VIP and PACAP share homology, they differ in their substrate specificities and expression patterns. See VIPR1 (MIM 192321) and ADCYAP1R1(MIM 102981).
  • Synonyms

    VIPR2; vasoactive intestinal peptide receptor 2; VPAC2; VPCAP2R; FLJ16511; vasoactive intestinal polypeptide receptor 2; VIP-R-2; PACAP-R3; PACAP-R-3; OTTHUMP00000200015; OTTHUMP00000200016; OTTHUMP00000200017; PACAP type III receptor; helodermin-preferring VIP receptor; pituitary adenylate cyclase-activating polypeptide type III receptor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Zebrafish
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • Fc
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human VIPR2-407H Recombinant Human VIPR2, Fc-tagged Human Cell Fc Met1-Val126
Human VIPR2-001HCL Recombinant Human VIPR2 cell lysate Human Cell N/A
Human VIPR2-2341H-B Recombinant Human VIPR2 Protein Pre-coupled Magnetic Beads HEK293
Human VIPR2-367H Recombinant Human VIPR2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human VIPR2-2341H Recombinant Human VIPR2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human VIPR2-2132HFL Recombinant Full Length Human VIPR2 Protein, C-Flag-tagged Mammalian cells Flag
Human VIPR2-2201H Recombinant Human VIPR2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse VIPR2-18022M Recombinant Mouse VIPR2 Protein Mammalian Cell His
Mouse VIPR2-10021M Recombinant Mouse VIPR2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse VIPR2-10021M-B Recombinant Mouse VIPR2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Vipr2-6924M Recombinant Mouse Vipr2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat VIPR2-6525R Recombinant Rat VIPR2 Protein Mammalian Cell His
Rat VIPR2-6181R-B Recombinant Rat VIPR2 Protein Pre-coupled Magnetic Beads HEK293
Rat VIPR2-6181R Recombinant Rat VIPR2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL34050HF Recombinant Full Length Human Vasoactive Intestinal Polypeptide Receptor 2(Vipr2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (24-438)
Mus musculus (Mouse) RFL5235MF Recombinant Full Length Mouse Vasoactive Intestinal Polypeptide Receptor 2(Vipr2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (23-437)
Rattus norvegicus (Rat) RFL5519RF Recombinant Full Length Rat Vasoactive Intestinal Polypeptide Receptor 2(Vipr2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (23-437)
Zebrafish VIPR2-9293Z Recombinant Zebrafish VIPR2 Mammalian Cell His
Chicken VIPR2-2175C Recombinant Chicken VIPR2 Mammalian Cell His
Kit-1038 Phagocytosis Assay Kit (Green E. coli) N/A
Kit-0948 Glucocorticoid Receptor Competitor Assay Kit, Green N/A
Kit-1543 cAMP VIPR2 CHO-K1 GPCR Assay Kit N/A
Kit-1544 VIPR2 CHO-K1 β-Arrestin GPCR Assay Kit N/A
Kit-1545 VIPR2 Total GPCR Internalization Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • VIPR2 Related Articles

VIPR2 involved in several pathways and played different roles in them. We selected most pathways VIPR2 participated on our site, such as cAMP signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with VIPR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
cAMP signaling pathwayCREB3L3;MAP2K1;GRIA3;PDE4A;ARAP3;HTR6;TNNI3;MAP2K2;RAF1
Neuroactive ligand-receptor interactionP2RY11;NPY8BR;TAAR7D;CSH;CHRNA10;HTR2CL1;PRP2;TAAR7F;TAAR14D

VIPR2 has several biochemical functions, for example, G-protein coupled receptor activity, vasoactive intestinal polypeptide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VIPR2 itself. We selected most functions VIPR2 had, and list some proteins which have the same functions with VIPR2. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityOLFCG4;GPR35;GPR39;S1PR5B;OLFR18;OR10C1;OR1L1;OR2J3;DRD7
vasoactive intestinal polypeptide receptor activityADCYAP1R1A;VIPR1B;GHRHRL;VIPR1;ADCYAP1R1;VIPR2

VIPR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VIPR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of VIPR2.

Hacd3; URM1

Shibata, M; Hisajima, T; et al. Morphological relationships between peptidergic nerve fibers and immunoglobulin A-producing lymphocytes in the mouse intestine. BRAIN BEHAVIOR AND IMMUNITY 22:158-166(2008).
Cassiman, D; Sinelli, N; et al. Human hepatic progenitor cells express vasoactive intestinal peptide receptor type 2 and receive nerve endings. LIVER INTERNATIONAL 27:323-328(2007).
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