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Vsig4

  • Official Full Name

    V-set and immunoglobulin domain containing 4

  • Overview

    This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.
  • Synonyms

    VSIG4; V-set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; Z39IG; protein Z39Ig; Ig superfamily protein; complement receptor of the immunoglobulin superfamily; CRIg;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • CHO
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293T
  • Human Cell
  • Mammalian cells
  • C
  • His
  • Fc
  • Avi
  • GST
  • hFc
  • His (Fc)
  • HlgG1 Fc
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human VSIG4-511H Active Recombinant Human VSIG4, HIgG1 Fc-tagged CHO Fc
Human VSIG4-510H Active Recombinant Human VSIG4, MIgG2a Fc-tagged CHO Fc
Human VSIG4-051H Active Recombinant Human VSIG4 protein, Fc/Avi-tagged, Biotinylated HEK293 cells Fc/Avi Arg20-Pro283
Human VSIG4-3955H Recombinant Human VSIG4, His tagged Human Cell His
Human VSIG4-423H Recombinant Human VSIG4, Fc tagged HEK293 Fc Met1-Pro283
Human VSIG4-055H Recombinant Human VSIG4 Protein, Fc-tagged HEK293 Fc
Human VSIG4-1092HCL Recombinant Human VSIG4 cell lysate Human Cell N/A
Human VSIG4-301419H Recombinant Human VSIG4 protein, GST-tagged E.coli GST Met305-Cys399
Human VSIG4-490H Recombinant Human VSIG4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human VSIG4-1277H Recombinant Human VSIG4 protein, hFc&His-tagged HEK293 hFc&His Arg20-Pro283
Human VSIG4-1161H Recombinant Human VSIG4 Protein (Met1-Pro283), HlgG1 Fc-tagged, Biotinylated HEK293 HlgG1 Fc Met1-Pro283
Human VSIG4-0817H Recombinant Human VSIG4 protein, His-tagged HEK293 His Arg20-Pro283
Human VSIG4-5593H Recombinant Human VSIG4 Protein (Met1-Pro187), C-His tagged Mammalian cells C-His Met1-Pro187
Mouse Vsig4-861M Active Recombinant Mouse Vsig4 Protein, Fc Chimera Mammalian cells Fc
Mouse Vsig4-2314M Recombinant Mouse Vsig4 protein, His-tagged HEK293 His Met1-Pro187
Mouse Vsig4-893M Recombinant Mouse Vsig4 protein, His&hFc-tagged HEK293 His&hFc Met1-Pro187
Mouse VSIG4-2519MCL Recombinant Mouse VSIG4 cell lysate Human Cell N/A
Mouse Vsig4-122M Recombinant Mouse Vsig4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Vsig4-6948M Recombinant Mouse Vsig4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Vsig4-122M-B Recombinant Mouse Vsig4 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Vsig4 Related Research Area

Vsig4 involved in several pathways and played different roles in them. We selected most pathways Vsig4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Vsig4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

Vsig4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Vsig4 itself. We selected most functions Vsig4 had, and list some proteins which have the same functions with Vsig4. You can find most of the proteins on our site.

Function Related Protein
protein bindingFATE1;PFDN5;ITGB1BP3;IL15;RPL30;MED28;NCBP2;MMS19;KIAA1967

Vsig4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Vsig4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Vsig4.

PDK2

  • Q&As
  • Reviews

Q&As (6)

Ask a question
What is the relationship of VSIG4 to other genes or proteins? 08/18/2022

VSIG4 has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.

How can the disease be treated by regulating the levels of VSIG4? 05/09/2022

There are no drugs that directly regulate VSIG4 levels, but they can affect VSIG4 expression and function by modulating the immune system.

How to detect and analyze mutations in VSIG4? 02/08/2022

Mutations in VSIG4 can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.

What is the specific role of VSIG4 in tumor immunity? 12/17/2020

VSIG4 plays an important role in tumor immunity, which can inhibit the activation and function of T cells and NK cells, thereby promoting tumor growth and metastasis.

How to study the regulatory mechanism of VSIG4? 06/05/2020

Studying the regulatory mechanism of VSIG4 requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

What are the mutation types of VSIG4? 05/08/2020

The types of mutations in VSIG4 include point mutations, insertions/deletions, duplications, etc., which can cause structural and functional abnormalities of the protein.

Customer Reviews (3)

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Reviews
11/08/2021

    Stable performance, excellent performance in a variety of experiments.

    10/01/2021

      No side effects, high safety.

      03/13/2021

        It has good antigenicity and can induce target immune response.

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