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WBP11

Official Full Name

WW domain binding protein 11
Overview

This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.
Synonyms

WBP11; WW domain binding protein 11; WW domain-binding protein 11; NPWBP; SIPP1; splicing factor; PQBP1 and PP1 interacting; DKFZp779M1063; MGC94547; Npw38 binding protein; Npw38 binding protein NpwBP; SH3 domain binding protein SNP70; SNP70; Splicing factor PQBP1 and PP1 interacting; WBP 11; Npw38-binding protein NpwBP; SH3 domain-binding protein SNP70; splicing factor, PQBP1 and PP1 interacting; splicing factor that interacts with PQBP-1 and PP1; WBP-11;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Rhesus Macaque
Zebrafish

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	WBP11-1920HCL	Recombinant Human WBP11 cell lysate		N/A	Inquiry
Mouse	WBP11-18432M	Recombinant Mouse WBP11 Protein	Mammalian Cell	His	Inquiry
Mouse	WBP11-10109M	Recombinant Mouse WBP11 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	WBP11-10109M-B	Recombinant Mouse WBP11 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	WBP11-6560R	Recombinant Rat WBP11 Protein	Mammalian Cell	His	Inquiry
Rat	WBP11-6216R	Recombinant Rat WBP11 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	WBP11-6216R-B	Recombinant Rat WBP11 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rhesus Macaque	WBP11-5186R	Recombinant Rhesus monkey WBP11 Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	WBP11-4999R	Recombinant Rhesus Macaque WBP11 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rhesus Macaque	WBP11-4999R-B	Recombinant Rhesus Macaque WBP11 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	WBP11-11680Z	Recombinant Zebrafish WBP11	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

WBP11 involved in several pathways and played different roles in them. We selected most pathways WBP11 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with WBP11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Spliceosome	THOC2;HNRNPA1B;PRPF4;FAM120B;SRSF1;SF3A1;SRSF7A;PQBP1;PHF5A

WBP11 has several biochemical functions, for example, WW domain binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WBP11 itself. We selected most functions WBP11 had, and list some proteins which have the same functions with WBP11. You can find most of the proteins on our site.

Function	Related Protein
WW domain binding	TRP63;TCEAL1;PMEPA1;WBP1;TCEAL8;TCEAL6;LITAF;ATCAY;NDFIP2
poly(A) RNA binding	ZYX;SRSF1;PTBP2;EBNA1BP2;HIST1H4F;Api5;RBM47;ATXN2L;MBNL1
protein binding	PRH1;CORO2B;ENOX1;LSAMP;HOXA1;CAMP;CLIC3;TUBGCP2;LAGE3
protein phosphatase type 1 regulator activity	UBXN2A;KCNS1;PHACTR3;PHACTR1;PHACTR3B;PPP1R7;PPP1R16A;WBP11;PPP1R15A
single-stranded DNA binding	ALYREF;BLM;TDP1;RAD23B;WBP11;MCM10;SSBP3;C10orf2;DMC1

WBP11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WBP11 here. Most of them are supplied by our site. Hope this information will be useful for your research of WBP11.

GRB2; PQBP1; q99ib8-pro_0000045603; FYN; TESC; TRAF4; PPP1CA