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Official Full Name
WD repeat and FYVE domain containing 3
This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.
ALFY; BWF1; Bchs; Ggtb3; ZFYVE25; AW319683; D5Ertd66e; mKIAA0993; B930017C24; 2610509D04Rik