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WFDC12
Official Full Name
WAP four-disulfide core domain 12
Background
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
Synonyms
WFDC12; WAP four-disulfide core domain 12; WAP four-disulfide core domain protein 12; whey acidic protein 2; elafin-like protein II; single WAP motif protein 2; WAP2; Swam2; MGC32134