WNT3
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Official Full Name
wingless-related MMTV integration site 3
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Overview
Defects in WNT3 are the cause of autosomal recessive tetra-amelia (ARTTRA). Tetra-amelia is a rare human genetic disorder characterized by complete absence of all four limbs and other anomalies such as craniofacial, nervous system, pulmonary, skeletal and urogenital defects. -
Synonyms
WNT3; wingless-related MMTV integration site 3; Int-4; Wnt-3; proto-oncogene Wnt-3; proto-oncogene Int-4; proto-oncogene protein Wnt-3;
- Recombinant Proteins
- Cell & Tissue Lysates
- Cattle
- Chicken
- Human
- Mouse
- Zebrafish
- CHO
- E. coli
- E.coli
- HEK293
- Human Cell
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- Yeast
- DDK
- GST
- His
- SUMO
- N/A
- N
- Strep II
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | WNT3-205H | Recombinant Human WNT3, StrepII-tagged | Human Cell | Strep II | 22-355, 334 a.a. |
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| Human | WNT3-5161H | Recombinant Human WNT3, GST-tagged | Wheat Germ | GST |
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| Human | WNT3-3738H | Recombinant Human WNT3, His-tagged | E.coli | His | 1-355aa | |
| Human | WNT3-296HCL | Recombinant Human WNT3 293 Cell Lysate | HEK293 | N/A |
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| Human | WNT3-549HF | Recombinant Full Length Human WNT3 Protein, GST-tagged | In Vitro Cell Free System | GST | 385 amino acids |
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| Human | WNT3-3739H | Recombinant Human WNT3 Protein, DDK-tagged | CHO | DDK |
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| Human | WNT3-3076H | Recombinant Human WNT3 protein, His-tagged | E.coli | His | 130-306 aa | |
| Mouse | WNT3-5160M | Active Recombinant Mouse WNT3 | N/A | |||
| Mouse | WNT3-5163M | Recombinant Mouse WNT3 Protein, His-SUMO-tagged | E. coli | His-SUMO | 22-355aa |
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| Mouse | WNT3-5164M | Recombinant Mouse WNT3 Protein, His-tagged | Yeast | His | 22–355aa |
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| Mouse | WNT3-5162M | Recombinant Mouse WNT3 Protein, His-tagged | E. coli | His | 22-355aa |
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| Cattle | WNT3-584C | Recombinant Cattle WNT3 Protein, His-tagged | E.coli | N-His | Val19-Lys355 |
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| Zebrafish | WNT3-6430Z | Recombinant Zebrafish WNT3 | Mammalian Cell | His |
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| Chicken | WNT3-3658C | Recombinant Chicken WNT3 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- WNT3 Related Articles
- WNT3 Related Gene Family
- WNT3 Related Signal Pathway
WNT3 involved in several pathways and played different roles in them. We selected most pathways WNT3 participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt signaling pathway | VANGL1;PORCNL;TLE3A;LEF1;WNT11;PLCB2;PPP3CCB;CAMK2D1;DVL3A |
| Hedgehog signaling pathway | WNT11B;GAS1A;PRKACAA;HHIP;WNT5B;BMP2;ZIC2A;WNT11R;WNT8A |
| Hippo signaling pathway | GSK3B;WNT6;WNT8B;WNT4;SMAD2;AFP;PPP2R2A;BMP5;LATS1 |
| Signaling pathways regulating pluripotency of stem cells | FZD5;PCGF2;FGFR2;WNT4;RAF1;BMPR1B;AKT1;FGFR1;BMPR1A |
| Melanogenesis | RAF1B;WNT11R;MAPK3;PLCB1;TCF7L2;FZD8A;FZD1;WNT4;WNT7AA |
| HTLV-I infection | VDAC1;MAP3K14;PCNA;HLA-DQA2;WNT3A;ITGB2L;SLC2A1;FZD2;SFPI1 |
| Pathways in cancer | ITGA3;IGF1;RHOA;BDKRB1;TGFBR1;PIK3R3;MSH6;TCF7L2;CTBP2 |
| Proteoglycans in cancer | PIK3R2;ITGAV;PTPN6;IGF1R;AKT1;HSPG2;CD44;GAB1;WNT9A |
| MicroRNAs in cancer | TP63;GLS2;DNMT3A;ST14;PDGFB;ZEB1;FZD3;CCNE2;DDIT4 |
| Basal cell carcinoma | WNT2B;FZD9;WNT8A;FZD10;TCF7L2;SUFU;GLI3;HHIP;BMP2 |
WNT3 has several biochemical functions, for example, frizzled binding, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT3 itself. We selected most functions WNT3 had, and list some proteins which have the same functions with WNT3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| frizzled binding | FZD1;WNT10B;RNF43;BAMBI;WNT2B;WNT1;DVL3;WNT16;RSPO3 |
| protein binding | RHOA;MT3;MC4R;PRKCQ;TMEM199;PPP4C;NAA30;TTC19;VAMP8 |
| protein domain specific binding | PRKCZ;NR0B2;KCNN2;CEP68;SFN;LIN7B;CNOT1;DDX6;LAMP1 |
| receptor agonist activity | WNT1;WNT4;WNT5A;WNT3;CXCL13;WNT8A;SFRP2;WNT10B;GREM1 |
WNT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT3.
FZD7
- Q&As
- Reviews
Q&As (5)
Ask a questionResearchers are exploring various approaches, including small molecules and biologics, to modulate WNT3 signaling for therapeutic benefits.
WNT3 can promote tissue regeneration by activating stem cells and facilitating tissue repair processes.
WNT3 can be explored in tissue engineering to enhance the development and integration of engineered tissues and organs.
WNT3 holds promise in regenerative medicine for its potential to enhance tissue regeneration, but more research is needed for practical applications.
Clinical trials may be investigating the role of WNT3 and related pathways in various diseases, but you would need to check the latest clinical trial databases for specific studies.
Customer Reviews (3)
Write a reviewI am extremely satisfied with the high performance and the exceptional support associated with this protein, as it has greatly contributed to the success of my scientific endeavors.
Their expertise and prompt assistance have been instrumental in overcoming challenges and optimizing the use of the WNT3 protein in my studies.
the manufacturer's commitment to delivering excellent technical support has proven to be invaluable in troubleshooting any issues that arose during my experiments.
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