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WNT4

  • Official Full Name

    wingless-related MMTV integration site 4

  • Overview

    The evolutionarily conserved WNT (Wingless-type MMTV integration site family) signaling pathway has diverse roles in governing cell fate, proliferation, migration, polarity and death. WNT signaling controls development and is important for embryogenesis a
  • Synonyms

    WNT4; wingless-related MMTV integration site 4; protein Wnt-4; signal molecule; Wnt-4; MGC123964; SERKAL;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • CHO
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human Cells
  • Mammalian Cell
  • GST
  • His
  • GST|His
  • hFc
  • His (Fc)
  • Avi
  • SUMO
  • N/A
  • N
  • Fc
  • Flag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human WNT4-516H Active Recombinant Human Wingless-Type MMTV Integration Site Family, Member 4 CHO N/A
Human WNT4-517HFL Recombinant Full Length Human WNT4 Protein, N-Fc-Flag-tagged HEK293T N-Fc-Flag Full Length
Human WNT4-3740H Recombinant Human WNT4, His-tagged E.coli His 1-351 aa
Human WNT4-413H Recombinant Human WNT4 Protein, GST/His-tagged E.coli GST/His
Human WNT4-294HCL Recombinant Human WNT4 293 Cell Lysate HEK293 N/A
Human WNT4-1891H Recombinant Human WNT4 protein, His-tagged E.coli His Leu26~Arg351
Human WNT4-01H Recombinant Human WNT4 Protein, His-tagged Human Cells His
Human WNT4-117H Active Recombinant Human WNT4 Protein E. coli
Human WNT4-3764H Recombinant Human WNT4 protein, His-SUMO-tagged E.coli His-SUMO 23-351aa
Human WNT4-1527H Recombinant Human WNT4 protein, hFc-tagged HEK293 hFc 23-351aa
Human WNT4-521HFL Recombinant Full Length Human WNT4 Protein, N-GST/C-His-tagged E.coli GST/His
Mouse Wnt4-622M Active Recombinant Mouse Wnt4 CHO N/A Ser23-Arg351
Mouse WNT4-18572M Recombinant Mouse WNT4 Protein Mammalian Cell His
Mouse WNT4-10197M Recombinant Mouse WNT4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse WNT4-10197M-B Recombinant Mouse WNT4 Protein Pre-coupled Magnetic Beads HEK293
Rat WNT4-6599R Recombinant Rat WNT4 Protein Mammalian Cell His
Rat WNT4-66R Recombinant Rat WNT4 Protein, His-tagged E.coli His Leu26~Arg351
Rat WNT4-6255R Recombinant Rat WNT4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat WNT4-6255R-B Recombinant Rat WNT4 Protein Pre-coupled Magnetic Beads HEK293
Chicken WNT4-6347C Recombinant Chicken WNT4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • WNT4 Related Articles
  • WNT4 Related Gene Family
  • WNT4 Related Research Area
  • WNT4 Related Signal Pathway

WNT4 involved in several pathways and played different roles in them. We selected most pathways WNT4 participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayFRAT2;DVL1B;RUVBL1;FZD9;SKP1;NLK;PRKCG;SFRP2;PPP3CCB
Hedgehog signaling pathwayRAB23;GLI2;GLI2B;WNT11;BMP4;WNT1;WNT3A;DYRK1A;GSK3B
Hippo signaling pathwayWNT1;BMP2;AFP;JUB;YWHAB;FBXW11;MOB1A;GLI2;WNT9B
Signaling pathways regulating pluripotency of stem cellsMAPK12;NODAL;KLF4;WNT7B;WNT2;SOX2;ACVR2B;HAND1;ID2
MelanogenesisNRAS;WNT3A;FZD10;a;FZD9B;GSK3B;PRKACG;PRKACBB;CALM4
Thyroid hormone signaling pathwayMED30;ATP1A3;KAT2A;PRKCB;PLCB1;ITGB3;NOTCH3;RXRA;DIO3
HTLV-I infectionAdcy4;Pdgfa&Pdgfb;CCND1;VDAC2;SFPI1;IL2RA;CCNB2;FZD3;LTA
Pathways in cancerLPAR6;WNT7A;FGF6;GNG3;WNT8A;STAT5A;CTBP2;AXIN2;FGF12
Proteoglycans in cancerWNT6;ITPR1;CD63;CAV2;GPC3;DROSHA;HPSE;PLCG2;MDM2
Basal cell carcinomaWNT3;FZD3;WNT5B;SMO;WNT8B;TCF7;GSK3B;WNT10B;FZD2

WNT4 has several biochemical functions, for example, frizzled binding, receptor agonist activity, transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT4 itself. We selected most functions WNT4 had, and list some proteins which have the same functions with WNT4. You can find most of the proteins on our site.

Function Related Protein
frizzled bindingCTHRC1;WNT7A;MYOC;WNT2BA;WNT9A;WNT5B;RSPO3;WNT11R;WNT6
receptor agonist activityWNT1;SFRP2;WNT4;NODAL;WNT3;WNT10B;WNT2;WNT5A;GAS6
transcription corepressor activitySKOR2;NCOR2;HDAC7;MXD4;SAP30;NANOG;SNW1;TRIB3;RCOR2

WNT4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT4 here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT4.

P2RX4

Morizane, R; Monkawa, T; et al. Kidney Specific Protein-Positive Cells Derived from Embryonic Stem Cells Reproduce Tubular Structures In Vitro and Differentiate into Renal Tubular Cells. PLOS ONE 8:-(2013).
Murugan, S; Shan, JD; et al. WT1 and Sox11 regulate synergistically the promoter of the Wnt4 gene that encodes a critical signal for nephrogenesis. EXPERIMENTAL CELL RESEARCH 318:1134-1145(2012).
WNT
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