WNT5B
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Official Full Name
wingless-type MMTV integration site family, member 5B
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Overview
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. -
Synonyms
WNT5B; wingless-type MMTV integration site family, member 5B; protein Wnt-5b; WNT-5B protein; MGC2648;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Cattle
- Chicken
- Human
- Mouse
- Zebrafish
- CHO
- E. coli
- E.coli
- HEK293
- Human Cell
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|T7
- N/A
- N
- GST
- Strep II
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | WNT5B-773H | Active Recombinant Human WNT5B | CHO | N/A | Gln18-Lys359 |
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| Human | WNT5B-207H | Recombinant Human WNT5B, StrepII-tagged | Human Cell | Strep II | 18-359, 342 a.a. |
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| Human | WNT5B-292HCL | Recombinant Human WNT5B 293 Cell Lysate | HEK293 | N/A |
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| Human | WNT5B-291HCL | Recombinant Human WNT5B 293 Cell Lysate | HEK293 | N/A |
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| Human | WNT5B-3053H | Recombinant Human WNT5B protein, His-tagged | E.coli | His | 128-267 aa | |
| Human | WNT5B-119H | Active Recombinant Human WNT5B Protein | E. coli |
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| Human | WNT5B-587H | Recombinant Human WNT5B Protein, His&GST-tagged | E.coli | N-His&GST | Gln18-Lys359 |
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| Mouse | Wnt5b-303M | Active Recombinant Mouse Wnt5b | CHO | N/A |
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| Mouse | WNT5B-18574M | Recombinant Mouse WNT5B Protein | Mammalian Cell | His |
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| Mouse | WNT5B-10199M-B | Recombinant Mouse WNT5B Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | WNT5B-10199M | Recombinant Mouse WNT5B Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Cattle | WNT5B-1478C | Recombinant Cattle WNT5B protein, His & T7-tagged | E.coli | His/T7 | Met30~Lys358 (Accession # F1MP15) |
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| Zebrafish | WNT5B-8578Z | Recombinant Zebrafish WNT5B | Mammalian Cell | His |
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| Chicken | WNT5B-3289C | Recombinant Chicken WNT5B | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- WNT5B Related Gene Family
- WNT5B Related Research Area
- WNT5B Related Signal Pathway
WNT5B involved in several pathways and played different roles in them. We selected most pathways WNT5B participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt signaling pathway | CAMK2D2;FZD7A;DAAM1B;MAPK9;NLK1;MAPK10;SIAH1;RAC1B;SIAH2L |
| Hedgehog signaling pathway | FBXW11;IHHB;WNT9B;SHHA;WNT11;IHHA;CSNK1G2B;WNT3A;BMP2B |
| Hippo signaling pathway | PPP2R1B;CTGF;CRB2;FZD8;WNT1;JUB;FZD6;GDF7;BMPR2 |
| Signaling pathways regulating pluripotency of stem cells | SMAD2;ISL1;AXIN2;ACVR1B;HAND1;PIK3CG;STAT3;APC;ZFHX3 |
| Melanogenesis | WNT1;PRKACAB;WNT9B;RAF1;GNAO1B;WNT7A;WNT7AA;CALM3B;FZD7 |
| HTLV-I infection | ANAPC5;BCL2L1;IKBKB;EGR1;CANX;MYBL1;TCF3;DVL2;HLA-DPA1 |
| Pathways in cancer | NKX3;PGF;GRB2;LAMA4;FGF22;GNAI1;AKT1;WNT6;AGTR1B |
| Proteoglycans in cancer | MAPK3;CBLB;FZD1;HPSE2;HPSE;ERBB4;ERBB2;RRAS2;AKT1 |
| Basal cell carcinoma | WNT10B;FZD1;PTCH2;DVL2;BMP4;FZD7;GLI3;WNT2B;TP53 |
WNT5B has several biochemical functions, for example, frizzled binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT5B itself. We selected most functions WNT5B had, and list some proteins which have the same functions with WNT5B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| frizzled binding | WNT2BA;WNT8A;WNT9B;WNT2B;WNT10B;DVL2;ZNRF3;DVL1;SFRP1 |
| receptor binding | FGF18B;TNFSF14;SSFA2;HCST;LAMA3;TNFSF8;HLA-A;KNG1;WNT4A |
WNT5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT5B here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT5B.
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