YAF2
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Official Full Name
YY1 associated factor 2
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Overview
The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple alternatively spliced transcript variants have been found for this gene. -
Synonyms
YAF2; YY1 associated factor 2; YY1-associated factor 2; MGC41856;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- Myc|DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | YAF2-3760H | Recombinant Human YAF2, His-tagged | E.coli | His | 1-204aa | |
| Human | YAF2-1943HCL | Recombinant Human YAF2 cell lysate | N/A |
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| Human | YAF2-157H | Recombinant Human YAF2 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK |
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| Mouse | Yaf2-7939M | Recombinant Mouse Yaf2 protein, His & T7-tagged | E.coli | His/T7 | Met1~His179 (Accession # Q99LW6) |
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| Mouse | YAF2-18647M | Recombinant Mouse YAF2 Protein | Mammalian Cell | His |
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| Mouse | YAF2-10246M | Recombinant Mouse YAF2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | Yaf2-7026M | Recombinant Mouse Yaf2 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Mouse | YAF2-10246M-B | Recombinant Mouse YAF2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | Yaf2-7940R | Recombinant Rat Yaf2 protein, His & T7-tagged | E.coli | His/T7 | Met1~His180 (Accession # D3ZII7) |
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| Rhesus Macaque | YAF2-5234R | Recombinant Rhesus monkey YAF2 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | YAF2-5047R | Recombinant Rhesus Macaque YAF2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rhesus Macaque | YAF2-5047R-B | Recombinant Rhesus Macaque YAF2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | YAF2-4267Z | Recombinant Zebrafish YAF2 | Mammalian Cell | His |
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| Chicken | YAF2-1775C | Recombinant Chicken YAF2 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- YAF2 Related Articles
YAF2 involved in several pathways and played different roles in them. We selected most pathways YAF2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with YAF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
YAF2 has several biochemical functions, for example, protein binding, transcription coactivator activity, transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by YAF2 itself. We selected most functions YAF2 had, and list some proteins which have the same functions with YAF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RBM44;HIST1H4B;PIK3IP1;SSX5;LILRB2;HACL1;C3orf52;VHL;ZC3H15 |
| transcription coactivator activity | WNT3A;RAN;PARK7;ACTL6A;MAGED1;SRA1;JUP;GTF2F1;CCNE1 |
| transcription corepressor activity | BCOR;NR0B1;PRMT5;SSX2;SETD8;HDAC5;ALX1;SFMBT1;SSX1 |
| zinc ion binding | SOLH;EWSR1B;ADAM7;CSRP3;FTR50;NR2F1A;GFI1AA;MUL1B;CA8 |
YAF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YAF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of YAF2.
RING1; XAGE1A; SETBP1; YY1; q7ard3_yerpe; asnB; chbG; Ring1; MYC; CSNK2A2; BMI1; PCGF2
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