YES1
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Official Full Name
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
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Overview
The cellular oncogene c-Yes and its viral homologue v-Yes (the transforming gene of Yamaguchi 73 and Esh avian sarcoma viruses) encode a 60 kDa, cytoplasmic, membrane-associated, protein-tyrosine kinase. Yes belongs to the Src kinase family and is ubiquit -
Synonyms
YES1; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1; tyrosine-protein kinase Yes; c yes; HsT441; Yes; proto-oncogene c-Yes; cellular yes-1 protein; Yamaguchi sarcoma oncogene; proto-oncogene tyrosine-protein kinase YES; c-yes; P61-YES;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Chicken
- Human
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Insect (sf21)
- Insect Cell
- Insect Cells
- Mammalian Cell
- Mammalian cells
- Sf21
- Sf9 Insect Cell
- DDK
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- Myc|DDK
- N/A
- N
- No tag
- Involved Pathway
- Protein Function
- Interacting Protein
- YES1 Related Research Area
YES1 involved in several pathways and played different roles in them. We selected most pathways YES1 participated on our site, such as Adherens junction, Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with YES1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Adherens junction | PTPRJ;FER;ACTN1;PVRL4;WASB;EGFR;PVRL3B;PTPRJA;FYN |
Tight junction | MLLT4;SHROOM2;MYH6;MYHZ2;CLDNB;ACTN3A;PTENA;CLDNF;MYH9 |
YES1 has several biochemical functions, for example, ATP binding, enzyme binding, epidermal growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by YES1 itself. We selected most functions YES1 had, and list some proteins which have the same functions with YES1. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | GSK3AA;RNASEL;TNK1;SMC1B;ABCB1;NSF;EPHA2A;STK35L;PFKFB4L |
enzyme binding | PDE4D;ATG3;MLL5;TTN;APOA1;GSTM2;STC2;PRKCA;CABYR |
epidermal growth factor receptor binding | LINGO1;PLSCR1;FER;HBEGF;TGFA;BTC;SHC1;SNX4;EPGN |
ion channel binding | SRI;CAV3;SUMO1;RNF207;KCNH1;FGF12;KCNQ3;RIMS3;FHL1 |
non-membrane spanning protein tyrosine kinase activity | FYNA;YES1;EIF2AK2;ZNF143B;ABL2;SYK;BTK;JAK3;STYK1 |
protein binding | FHL1;TMEM41A;MRAS;VAMP2;GADD45A;DULLARD;TBC1D23;MEF2D;TTC25 |
protein tyrosine kinase activity | TYRO3;Fert2;EPHB2;NTRK2B;FGFR1;MAP3K11;INSRA;EPHA4B;TYK2 |
receptor binding | FGF13B;HIST2H3C2;JAK2;MLN;KCNJ10;FASLG;FGF11;PPP2R4;NMU |
YES1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YES1 here. Most of them are supplied by our site. Hope this information will be useful for your research of YES1.
OLIG1; PTK2; SOCS3; EGFR; FXR2; TRAF2; C1orf94
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