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YWHAH

  • Official Full Name

    Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Eta Polypeptide

  • Overview

    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.
  • Synonyms

    YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; YWHA1; 14-3-3 eta; Protein AS1; 14-3-3 protein eta; OTTHUMP00000028905;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human YWHAH-26005TH Recombinant Human YWHAH, His-tagged E.coli His 246 amino acids
Human YWHAH-2562H Recombinant Human YWHAH protein(Gly2-Asn246), GST-tagged E. coli N-GST Gly2-Asn246
Human YWHAH-142H Recombinant Human YWHAH Protein, GST-tagged E.coli GST
Human YWHAH-26007TH Recombinant Human YWHAH, His-tagged E.coli His 246 amino acids
Human YWHAH-67H Recombinant Human YWHAH protein E.coli N/A
Human YWHAH-141H Recombinant Human YWHAH Protein E.coli N/A
Human YWHAH-139H Recombinant Human YWHAH Protein, His-tagged Insect Cell His
Human YWHAH-143H Recombinant Human YWHAH Protein, GST-tagged E.coli GST
Human YWHAH-231HCL Recombinant Human YWHAH 293 Cell Lysate HEK293 N/A
Human YWHAH-2380H Recombinant Human YWHAH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human YWHAH-871H Recombinant Human YWHAH Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human YWHAH-5176H Recombinant Human YWHAH protein, GST-tagged E.coli GST 4-246aa
Human YWHAH-2380H-B Recombinant Human YWHAH Protein Pre-coupled Magnetic Beads HEK293
Human YWHAH-922HFL Recombinant Full Length Human YWHAH Protein, C-Flag-tagged Mammalian cells Flag
Mouse YWHAH-18685M Recombinant Mouse YWHAH Protein Mammalian Cell His
Mouse Ywhah-140M Recombinant Mouse Ywhah Protein, His-tagged Insect Cell His
Mouse YWHAH-10270M-B Recombinant Mouse YWHAH Protein Pre-coupled Magnetic Beads HEK293
Mouse YWHAH-10270M Recombinant Mouse YWHAH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ywhah-7042M Recombinant Mouse Ywhah Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat YWHAH-6640R Recombinant Rat YWHAH Protein Mammalian Cell His
Rat YWHAH-6296R Recombinant Rat YWHAH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat YWHAH-6296R-B Recombinant Rat YWHAH Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque YWHAH-5248R Recombinant Rhesus monkey YWHAH Protein, His-tagged Mammalian Cell His
Rhesus Macaque YWHAH-5061R Recombinant Rhesus Macaque YWHAH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque YWHAH-5061R-B Recombinant Rhesus Macaque YWHAH Protein Pre-coupled Magnetic Beads HEK293
Zebrafish YWHAH-12380Z Recombinant Zebrafish YWHAH Mammalian Cell His
Chicken YWHAH-1764C Recombinant Chicken YWHAH Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • YWHAH Related Research Area

YWHAH involved in several pathways and played different roles in them. We selected most pathways YWHAH participated on our site, such as Cell cycle, Oocyte meiosis, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with YWHAH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell cycleRAD17;EP300;ODF2;GSK3B;SMC3;DBF4;DCTN1;PANE1;GORASP1
Oocyte meiosisRBX1;PPP2R5D;SPDYA;RPS6KA3B;YWHAG;CDC26;MAPK3;CAMK2B;PPP3R2
PIK-Akt signaling pathwayCREB3L1;NFKB1;IFNA17;STK11;PPP2R2A;ITGB8;IRS1;IL6R;KIT
Hippo signaling pathwayMOB1A;FBXW11;ACTB;SMAD2;FZD3;TEAD3;TGFBR2;PARD3;RASSF1
Epstein-Barr virus infectionTBK1;LYN;HLA-DQB1;POLR2E;MAPK9;HLA-F;MAPK8;NUP214;MAP2K3
Viral carcinogenesisHIST1H4I;PIK3CA;HIST1H2BK;TTC6;MAPK1;HIST1H4N;RBL2;HIST1H2BF;HIST1H4E

YWHAH has several biochemical functions, for example, actin binding, enzyme binding, glucocorticoid receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by YWHAH itself. We selected most functions YWHAH had, and list some proteins which have the same functions with YWHAH. You can find most of the proteins on our site.

Function Related Protein
actin bindingCNN1;MSRB1A;DBNL;MYHZ1.1;CAPZA1B;MYH9A;ABLIM1;WASH1;FLII
enzyme bindingSNRPD3;PPARG;GNB2L1;HIST1H2AM;CYP2A4;PICK1;GOT2;PEBP1;ACAT1
glucocorticoid receptor bindingSTAT5B;FKBP4;NR4A2;GRIP1;STAT3;EP300;YWHAH;NRIP1;ETS2
insulin-like growth factor receptor bindingINSL4;IGF2A;IRS1;YWHAH;REN;GNAS;ARRB1;INS2;IGF1
ion channel bindingPKP2;KCNB1;FHL1;CDH5;CHERP;KCNJ11;ANK2;YWHAQ;CALM1
protein bindingUSP33;TTLL6;TCEAL5;TAF9;ZNF259;DEPDC1;ZNHIT1;METTL13;DTNB
protein domain specific bindingMTOR;STAMBP;XPO1;ICAL1;IGBP1;HIST2H4A;YWHAE;TADA3;EZR
protein heterodimerization activityNR2C2;NOTCH4;RAF1;H2AFB1;GUCY1A3;SDCBP2;HOMER2;SUPT3H;MEF2A
sodium channel regulator activityFGF12;SGK3;SCN1BA;SCN2B;FGF13;FXYD6;FXYD4;SGK2A;FXYD2

YWHAH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YWHAH here. Most of them are supplied by our site. Hope this information will be useful for your research of YWHAH.

MARK2; RAF1; HDAC4; CDC25B

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