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ZHX1

Official Full Name

zinc fingers and homeoboxes 1
Overview

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene.
Synonyms

ZHX1; zinc fingers and homeoboxes 1; zinc fingers and homeoboxes protein 1; ZHX 1; ZHX-1; ZHX1_HUMAN; Zinc finger and homeodomain protein 1; Zinc fingers and homeobox 1; OTTHUMP00000228386; OTTHUMP00000228389;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Rhesus Macaque

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ZHX1-3809H	Recombinant Human ZHX1, GST-tagged	E.coli	GST	16-307aa	$319 / 25ug
Human	ZHX1-1982HCL	Recombinant Human ZHX1 cell lysate		N/A		Inquiry
Mouse	ZHX1-19173M	Recombinant Mouse ZHX1 Protein	Mammalian Cell	His		Inquiry
Mouse	ZHX1-10377M	Recombinant Mouse ZHX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	ZHX1-10377M-B	Recombinant Mouse ZHX1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	ZHX1-6706R	Recombinant Rat ZHX1 Protein	Mammalian Cell	His		Inquiry
Rat	ZHX1-6338R-B	Recombinant Rat ZHX1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	ZHX1-6338R	Recombinant Rat ZHX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	ZHX1-5292R	Recombinant Rhesus monkey ZHX1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	ZHX1-5105R	Recombinant Rhesus Macaque ZHX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	ZHX1-5105R-B	Recombinant Rhesus Macaque ZHX1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

ZHX1 involved in several pathways and played different roles in them. We selected most pathways ZHX1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZHX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ZHX1 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZHX1 itself. We selected most functions ZHX1 had, and list some proteins which have the same functions with ZHX1. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	TCEA2;YEATS4;TEAD3;BRD4;LHX2A;IGHMBP2;HOMEZ;PUF60;LASS5
metal ion binding	ITGA2;GALNT5;GM5136;ZFP653;PPM1F;ADNPA;STK32A;ZNF571;CECR1A
protein binding	NFKBIB;ARHGEF15;RSPH1;SLIRP;PNMA1;TAF8;TMEM123;PRMT5;TLX3
protein heterodimerization activity	IL12A;MAPK4;SNX5;H2AFVA;TCF3A;ANO2;CA;DLG4B;PDGFA
transcription corepressor activity	E4F1;YAF2;CCND1;TRIM28;BASP1;TBL1XR1B;MAP3K10;TFAP2B;HSBP1
transcription factor activity, sequence-specific DNA binding	HOXB8B;ZFP518A;FOXA;EGR2B;HEYL;CTBP1;GLIS2;KLF7;POU2F1B

ZHX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZHX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZHX1.

DNMT3B; ZHX2; ATXN1; NR3C1; PSMD11; BHLHE40; TNFRSF10C; PEX14; PRPF40A; IDH1