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ZHX3

  • Official Full Name

    zinc fingers and homeoboxes 3

  • Overview

    This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor.
  • Synonyms

    ZHX3; zinc fingers and homeoboxes 3; TIX1, triple homeobox 1; zinc fingers and homeoboxes protein 3; KIAA0395; triple homeobox 1; triple homeobox protein 1; zinc finger and homeodomain protein 3; TIX1;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ZHX3-1983HCL Recombinant Human ZHX3 cell lysate N/A
Human ZHX3-3721H Recombinant Human ZHX3 protein, GST-tagged E.coli GST 848-956 aa
Mouse Zhx3-7108M Recombinant Mouse Zhx3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat ZHX3-6707R Recombinant Rat ZHX3 Protein Mammalian Cell His
Rat ZHX3-6339R Recombinant Rat ZHX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ZHX3-6339R-B Recombinant Rat ZHX3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ZHX3-5293R Recombinant Rhesus monkey ZHX3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ZHX3-5106R Recombinant Rhesus Macaque ZHX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ZHX3-5106R-B Recombinant Rhesus Macaque ZHX3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ZHX3-9847Z Recombinant Zebrafish ZHX3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ZHX3 Related Articles

ZHX3 involved in several pathways and played different roles in them. We selected most pathways ZHX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZHX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ZHX3 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZHX3 itself. We selected most functions ZHX3 had, and list some proteins which have the same functions with ZHX3. You can find most of the proteins on our site.

Function Related Protein
DNA bindingRNF11;RCOR2;ZNF32;GM239;SRFA;EGR2B;MEF2AA;ZNF131;TOP1
metal ion bindingTRIM36;GM5077;ZNF185;PRLR;DYRK4;TRMT44;ZNF829;RPE;SP3
protein bindingSH3GL2;RNF149;TFRC;TCF7;RAB3A;ZFP36L1;CHD1;FAM54B;DOK6
protein heterodimerization activityPML;UBXN6;TP53;CENPW;ENO3;ALG2;TLR1;HIST1H2BE;HIST1H4A
protein homodimerization activitySLC26A5;ATPIF1B;ENG;TDG;PLEK;APOA1BP;PVRL1A;S100A1;TYR
transcription corepressor activityKDM5B;CTBP2A;ZNF274;SMYD1;CBFA2T2;NR2F2;HAND1;DNMT3B;TRIM28
transcription factor activity, sequence-specific DNA bindingZKSCAN17;YY1;RHOXF1;DMRTC1B;KDM1A;SOX11B;ZNF354B;HLFA;RORA

ZHX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZHX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZHX3.

NLK; ATXN1; q8ckl9_yerpe; q9wmx2-pro_0000037548; mdm2_human_probe

Lee, JH; Nam, H; et al. Upregulation of GM-CSF by TGF-beta 1 in epithelial mesenchymal transition of human HERS/ERM cells. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 50:399-405(2014).
Chaudhry, P; Fabi, F; et al. Prostate apoptosis response-4 mediates TGF-beta-induced epithelial-to-mesenchymal transition. CELL DEATH & DISEASE 5:-(2014).
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