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ZMYM2

Official Full Name

zinc finger, MYM-type 2
Overview

The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
Synonyms

ZMYM2; zinc finger, MYM-type 2; FIM; MYM; RAMP; SCLL; ZNF198; zinc finger MYM-type protein 2; zinc finger protein 198; fused in myeloproliferative disorders protein; rearranged in an atypical myeloproliferative disorder;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Mouse
Rhesus Macaque

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	ZMYM2-19200M	Recombinant Mouse ZMYM2 Protein	Mammalian Cell	His	Inquiry
Mouse	ZMYM2-10391M-B	Recombinant Mouse ZMYM2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	ZMYM2-10391M	Recombinant Mouse ZMYM2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rhesus Macaque	ZMYM2-5299R	Recombinant Rhesus monkey ZMYM2 Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	ZMYM2-5112R	Recombinant Rhesus Macaque ZMYM2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rhesus Macaque	ZMYM2-5112R-B	Recombinant Rhesus Macaque ZMYM2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ZMYM2 Related Articles

ZMYM2 involved in several pathways and played different roles in them. We selected most pathways ZMYM2 participated on our site, such as PluriNetWork, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZMYM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
PluriNetWork	KLF5;XPO4;ZFP143;RCOR2;ZMYM2;IPO7;ZSCAN10;ZFP57;SALL3

ZMYM2 has several biochemical functions, for example, metal ion binding, protein binding, ubiquitin conjugating enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZMYM2 itself. We selected most functions ZMYM2 had, and list some proteins which have the same functions with ZMYM2. You can find most of the proteins on our site.

Function	Related Protein
metal ion binding	ZFP28;SOBP;CYP2K18;ITGB1BP3;TMPPE;ZNF821;NRXN1A;ZNF507;KDM5D
protein binding	SLC1A5;FAM54B;EFNA4;SEPT3;MYL2;CCND2;HBZ;ZFYVE19;LNX2B
ubiquitin conjugating enzyme binding	RNF180;TCHP;TOLLIP;FOXL2;DCUN1D3;DCUN1D4;RNF144B;RNF144A;RNF14
zinc ion binding	SPG7;ZDHHC6;ZDHHC15B;PDLIM4;MGRN1A;TRIM109;RORC;AJUBA;ADAM32

ZMYM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZMYM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZMYM2.

Nanog; Pou5f1

Guzzo, CM; Ringel, A; et al. Characterization of the SUMO-Binding Activity of the Myeloproliferative and Mental Retardation (MYM)-Type Zinc Fingers in ZNF261 and ZNF198. PLOS ONE 9:-(2014).

Nam, SW; Park, KC; et al. Identification of Zinc Finger, MYM-type 2 (ZMYM2) as a regulator of sorafenib resistance in hepatocellular carcinoma cell lines. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 29:633-639(2014).