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ZNF473

  • Official Full Name

    zinc finger protein 473

  • Overview

    Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.
  • Synonyms

    ZNF473; zinc finger protein 473; ZN473; HZFP100; zfp-100; zinc finger protein ZFP100; zinc finger protein 100 homolog; Zfp 100; ZNF 473; 4932441F21; D030014N22Rik;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ZNF473-2033HCL Recombinant Human ZNF473 cell lysate N/A
Human ZNF473-301199H Recombinant Human ZNF473 protein, GST-tagged E.coli GST Met1-Glu204
Human ZNF473-582H Recombinant Human ZNF473 Protein, His-tagged E.coli His
Mouse ZFP473-18953M Recombinant Mouse ZFP473 Protein Mammalian Cell His
Mouse ZNF473-10429M-B Recombinant Mouse ZNF473 Protein Pre-coupled Magnetic Beads HEK293
Mouse ZNF473-10429M Recombinant Mouse ZNF473 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ZNF473-5333R Recombinant Rhesus monkey ZNF473 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ZNF473-5146R Recombinant Rhesus Macaque ZNF473 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ZNF473-5146R-B Recombinant Rhesus Macaque ZNF473 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ZNF473 Related Articles

ZNF473 involved in several pathways and played different roles in them. We selected most pathways ZNF473 participated on our site, such as Cleavage of Growing Transcript in the Termination Region, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF473 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cleavage of Growing Transcript in the Termination RegionLSM10;U2AF2;SRSF11;THOC4;LSM11;ZFP473;CSTF1;CLP1;CSTF3
Gene ExpressionZNF613;ZNF747;ZNF692;ZNF189;TBX5;TET2;TAF1D;PRMT5;HNRNPL2
Generic Transcription PathwayZNF615;ZNF691;ZNF557;ZNF225;SCO1;ZNF167;ESRRA;ZNF560;RRAGA
Processing of Capped Intronless Pre-mRNACSTF1;PAPOLA;LSM11;CSTF3;CLP1;NUDT21;ZNF473;ZFP473;SLBP
RNA Polymerase II TranscriptionTHOC4;SUPT16H;CCNT2A;CCNT2B;LSM11;SRSF11;LSM10;SSRP1A;RNPS1
RNA Polymerase II Transcription TerminationTHOC4;SRSF11;CSTF2;CSTF3;RNPS1;LSM10;NUDT21;CLP1;U2AF2
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAsSLBP;ZNF473;ZFP473;LSM10;LSM11
SLBP independent Processing of Histone Pre-mRNAsZFP473;LSM10;LSM11;ZNF473

ZNF473 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF473 itself. We selected most functions ZNF473 had, and list some proteins which have the same functions with ZNF473. You can find most of the proteins on our site.

Function Related Protein
DNA bindingMCMDC2;ARID3B;ZNF2;ZFP57;NEUROD6;ZNF485;FOXG1A;ZNF560;BRPF1
metal ion bindingPDE1A;PDE4C;PDE3A;FCNA;TRIM109;ZFYVE21;FAHD2A;ZNF227;SMYD2B
protein bindingCOMMD8;DPYSL2;PPP1R16B;MIS12;CXorf48;MPP6;C20orf195;L3MBTL1;SYT1

ZNF473 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF473 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF473.

RNPS1; ZSCAN12; ZNF250; CLK2; KRTAP10-8; KRTAP10-9; ZNF792

Hu, C; Zhang, SP; et al. Roles of Kruppel-associated Box (KRAB)-associated Co-repressor KAP1 Ser-473 Phosphorylation in DNA Damage Response. JOURNAL OF BIOLOGICAL CHEMISTRY 287:18937-18952(2012).
White, D; Rafalska-Metcalf, IU; et al. The ATM Substrate KAP1 Controls DNA Repair in Heterochromatin: Regulation by HP1 Proteins and Serine 473/824 Phosphorylation. MOLECULAR CANCER RESEARCH 10:401-414(2012).
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