AGR3
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Official Full Name
anterior gradient 3 homolog
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Overview
Anterior gradient protein 3 homolog is a protein that in humans is encoded by the AGR3 gene. -
Synonyms
AGR3; anterior gradient 3 homolog (Xenopus laevis); anterior gradient protein 3 homolog; BCMP11; breast cancer membrane protein 11; hAG 3; HAG3; PDIA18; protein disulfide isomerase family A; member 18; AG-3; anterior gradient homolog 3; protein disulfide;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Human
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- Fc
- GST
- HIS
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
AGR3 involved in several pathways and played different roles in them. We selected most pathways AGR3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AGR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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AGR3 has several biochemical functions, for example, dystroglycan binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AGR3 itself. We selected most functions AGR3 had, and list some proteins which have the same functions with AGR3. You can find most of the proteins on our site.
Function | Related Protein |
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dystroglycan binding | DAG1;AGR2;MAP2;AGR3;DMD;CLASP1;AGRN;GYLTL1B;VCL |
protein binding | TNFAIP1;STAT5A;FAM158A;PPP2R2B;RHOJ;FBXO18;VARS2;ZC3H15;ABTB1 |
AGR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of AGR3.
SGTA; ERLIN1; NUP62; UBQLN1; BCAR3; TGFB1; PTPN1; APC; AKT1; CASP8; ASB10; ESR2
- Q&As
- Reviews
Q&As (10)
Ask a questionThe interaction partners of AGR3 can be identified using techniques such as co-immunoprecipitation (Co-IP), yeast two-hybrid assays, or proximity-dependent biotin identification (BioID).
AGR3 is thought to promote cancer cell survival, proliferation, and metastasis by modulating cellular signaling pathways and interacting with other proteins involved in cancer progression.
The exact mechanisms are still being elucidated, but AGR3 has been shown to interact with proteins involved in cell adhesion, invasion, and apoptosis, contributing to cancer phenotypes.
AGR3 protein samples should be stored at -80°C to maintain their stability and prevent degradation. It is advisable to aliquot the protein to avoid repeated freeze-thaw cycles.
The purification of AGR3 protein can be achieved through techniques such as affinity chromatography, size-exclusion chromatography, or ion-exchange chromatography.
AGR3 expression is regulated by androgen receptor signaling in prostate cancer cells, and it may play a role in mediating androgen-dependent growth and survival.
Targeting AGR3 is an area of active research, and potential strategies such as small molecule inhibitors or immunotherapies are being explored for therapeutic interventions.
AGR3 expression can be detected and quantified using techniques such as immunohistochemistry, immunoblotting, and molecular assays like quantitative PCR (qPCR) or RNA sequencing.
Limited animal models, such as mouse models, have been utilized to study AGR3 function in specific tissues or diseases, providing insights into its physiological roles.
Similar to AGR2, AGR3 can be secreted into the extracellular space, where it may interact with other proteins and potentially influence cell signaling and behavior.
Customer Reviews (5)
Write a reviewI would appreciate more detailed documentation accompanying the product.
The proteins offered by this company are of exceptional quality and come at an affordable price, making them an excellent choice for my research needs.
The customer service was exceptional, with prompt assistance and valuable technical support.
This product exceeded my expectations in terms of quality.
This protein helo me to continue my experiments without breaking the bank.
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