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copA

Official Full Name

coatomer protein complex subunit alpha
Overview

In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by;non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent;subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP,;delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the;alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive;peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative;splicing results in multiple splice forms encoding distinct isoforms.
Synonyms

COPA; coatomer protein complex subunit alpha; Alpha coat protein; Alpha COP; Alpha COPI; AlphaCOP; Coatomer subunit alpha; COP A; COP I alpha; COPI alpha; FLJ26320; HEP COP; HEPCOP; Proxenin; Xenin; Xenopsin-related peptide;

Type

Recombinant Proteins

Species

B.subtilis
Bacillus subtilis
Chicken
Human
Zebrafish

Source

E. coli or Yeast
E.coli
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	COPA-1691H	Recombinant Human COPA Protein, GST-tagged	Wheat Germ	GST	Inquiry
B.subtilis	copA-442B	Recombinant B.subtilis Copper Transporter ATPase, Domain A+B	E.coli	N/A	Inquiry
B.subtilis	copA-440B	Recombinant B.subtilis Copper Transporter ATPase, Domain A	E.coli	N/A	Inquiry
B.subtilis	copA-441B	Recombinant B.subtilis Copper Transporter ATPase, Domain B	E.coli	N/A	Inquiry
Bacillus subtilis	COPA-0071B	Recombinant Bacillus subtilis COPA protein, His-tagged	E. coli or Yeast	His	Inquiry
Zebrafish	COPA-262Z	Recombinant Zebrafish COPA	Mammalian Cell	His	Inquiry
Chicken	COPA-3056C	Recombinant Chicken COPA	Mammalian Cell	His	Inquiry

copA Related Articles

copA involved in several pathways and played different roles in them. We selected most pathways copA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with copA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

copA has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by copA itself. We selected most functions copA had, and list some proteins which have the same functions with copA. You can find most of the proteins on our site.

Function	Related Protein

copA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with copA here. Most of them are supplied by our site. Hope this information will be useful for your research of copA.

Preisig, O; Zufferey, R; et al. The Bradyrhizobium japonicum fixGHIS genes are required for the formation of the high-affinity cbb(3)-type cytochrome oxidase. ARCHIVES OF MICROBIOLOGY 165:297-305(1996).

ODERMATT, A; KRAPF, R; et al. INDUCTION OF THE PUTATIVE COPPER ATPASES, COPA AND COPB, OF ENTEROCOCCUS-HIRAE BY AG+ AND CU2+, AND AG+ EXTRUSION BY COPB. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 202:44-48(1994).

ODERMATT, A; SUTER, H; et al. PRIMARY STRUCTURE OF 2 P-TYPE ATPASES INVOLVED IN COPPER HOMEOSTASIS IN ENTEROCOCCUS-HIRAE. JOURNAL OF BIOLOGICAL CHEMISTRY 268:12775-12779(1993).