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CSF1

  • Official Full Name

    colony stimulating factor 1 (macrophage)

  • Overview

    Macrophage colony-stimulating factor, or M-CSF, is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. (See colony-stimulating factor.) M-CSF binds to the Colony stimulating factor 1 receptor. It may also be involved in development of the placenta.
  • Synonyms

    CSF1; colony stimulating factor 1 (macrophage); MCSF; MGC31930; macrophage colony-stimulating factor 1; CSF-1; lanimostim; OTTHUMP00000013362; OTTHUMP00000013363; OTTHUMP00000013364; OTTHUMP00000013365; macrophage colony stimulating factor; M-CSF;

  • Recombinant Proteins
  • GMP Proteins
  • Cell & Tissue Lysates
  • Transfected Stable Cell Lines
  • Bovine
  • Chicken
  • Cynomolgus
  • Cynomolgus/Rhesus
  • Homo sapiens (Human)
  • Human
  • Human, Cynomolgus
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • B.mori
  • Barley Grain
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293F
  • HEK293T
  • Hordeum Vulgare
  • Human
  • Human Cell
  • Human cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Silkworm
  • Wheat Germ
  • Yeast
  • C
  • His
  • Myc
  • DDK
  • Fc
  • GST
  • His(C
  • ter)
  • His|GST
  • His|S
  • Avi
  • MYC
  • Myc|DDK
  • N/A
  • N
  • Strep II
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CSF1-426H Active Recombinant Human CSF1 Protein, His-tagged Yeast His
Human CSF1-167H Active Recombinant Human Colony Stimulating Factor 1 (Macrophage) HEK293 N/A
Human CSF1-418H Active Recombinant Human CSF1 Silkworm N/A
Human CSF1-033E Active Recombinant Human CSF1 (33-190aa), Met tagged E.coli N/A
Human CSF1-427H Active Recombinant Human CSF1 Protein HEK293 N/A
Human CSF1-565H Active Recombinant Human CSF1 protein, His-tagged HEK293 His Met1-Asn190
Human CSF1-32H Active Recombinant Human CSF1, His-tagged Barley Grain His
Human CSF1-424H Active Recombinant Human CSF1 Protein, Fc-tagged HEK293 Fc Met1-Arg255
Human CSF1-18HG Active Recombinant Human CSF1 Protein (Glu33-Ser190), GMP Grade, Animal-Free E.coli Glu33-Ser190
Human CSF1-12H Active Recombinant Human CSF1 Protein, Pre-aliquoted E.coli Glu33-Ser190, with an N-terminal Met
Human CSF1-110HG Active GMP Recombinant Human CSF1 Protein E.coli N/A
Human CSF1-420H Active Recombinant Human CSF1 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Glu 33 - Arg 255
Human CSF1-3279H Active Recombinant Human CSF1 protein(Met1-Arg255), His-tagged HEK293 C-His Met1-Arg255
Human CSF1-1962H Recombinant Human CSF1 Protein, GST-tagged Wheat Germ GST
Human CSF1-96H Recombinant Human CSF1, His-tagged E.coli His
Human CSF1-177H Recombinant Human CSF1 Protein, Mature chain, Tag Free, Biotinylated B.mori Tag Free Mature chain
Human CSF1-5383H Recombinant Human Colony Stimulating Factor 1 (macrophage) Hordeum Vulgare N/A
Human CSF1-425H Recombinant Human CSF1 protein, His-tagged HEK293 His Glu33-Arg255
Human CSF1-357H Recombinant Human Colony Stimulating Factor 1 (macrophage) Human N/A
Human CSF1-698H Recombinant Human CSF1 protein, His & GST-tagged E.coli His/GST Glu33~Ser496
Human CSF1-339H Recombinant Human Colony Stimulating Factor 1 (macrophage) Human N/A
Human CSF1-289H Recombinant Human CSF1 protein E.coli N/A 158
Human CSF1-26835TH Recombinant Human CSF1, His-tagged His
Human CSF1-1875H Recombinant Human Colony Stimulating Factor 1 (macrophage) HEK293 N/A
Human CSF1-216H Recombinant Human CSF1, StrepII-tagged Human Cell Strep II 33-191, 159 a.a.
Human CSF1-1934HCL Recombinant Human CSF1 cell lysate Human Cell N/A
Human CSF1-427HB Recombinant Human CSF1 protein, His-tagged, Biotinylated HEK293 His Met1-Asn190
Human CSF1-2158H Recombinant Human CSF1 Protein, His-tagged E.coli N-His Glu33-Ser496
Human CSF1-3337H Recombinant Human CSF1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CSF1-198H Recombinant Human CSF1 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human CSF1-45H Recombinant Active Human CSF1 Protein, His-tagged(C-ter) E.coli His(C-ter)
Human CSF1-2160H Recombinant Human CSF1 Protein, His-tagged E.coli N-His Glu33-Asn190
Human CSF1-4448H Recombinant Human CSF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CSF1-4319H Recombinant Human CSF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CSF1-4027H Recombinant Human CSF1 Protein (Glu33-Arg255), C-His tagged Mammalian cells C-His Glu33-Arg255
Human CSF1-5384H Recombinant Human CSF1 protein, His-tagged Yeast His 33-554aa
Human CSF1-2156HF Recombinant Full Length Human CSF1 Protein, GST-tagged In Vitro Cell Free System GST 554 amino acids
Human CSF1-6225H Recombinant Human CSF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CSF1-4028H Recombinant Human CSF1 Protein (Glu33-Arg255), N-His tagged Mammalian cells N-His Glu33-Arg255
Human CSF1-94H Human Macrophage Colony Stimulating Factor(rDNA derived) Reference standard N/A
Human CSF1-521H Recombinant Human CSF1 Protein 554
Human CSF1-335C Active Recombinant Human CSF1 Protein (159 aa) E.coli 159
Human CSF1-41H Active Recombinant Human CSF1 Protein, Animal Free Human cells
Human CSF1-27H Active Recombinant Human CSF1 Protein (Glu33-Ser190), C-His tagged, Animal-free, Carrier-free E.coli C-His Glu33-Ser190
Human CSF1-083C Active Recombinant Human CSF1 Protein (1-149 aa) Silkworm 1-149
Human CSF1-603H Recombinant Human CSF1 protein, His-Avi-tagged HEK293 His-Avi Glu33-Asn190
Human CSF1-40H Active Recombinant Human CSF1 Protein E.coli
Human CSF1-223C Active Recombinant Human CSF1 Protein CHO
Human CSF1-2521H Recombinant Human CSF1 Protein (Glu33-Ser496), His tagged E.coli His Glu33-Ser496
Mouse Csf1-290M Active Recombinant Mouse Csf1 protein E.coli N/A 156 amino acid
Mouse CSF1-414M Active Recombinant Mouse CSF1 protein(Met1-Glu262), His-tagged HEK293 C-His Met1-Glu262
Mouse Csf1-522M Active Recombinant Mouse Csf1 protein HEK293 N/A Met1-Glu262
Mouse Csf1-041E Active Recombinant Mouse Csf1 (33-262aa), Met tagged E.coli N/A
Mouse Csf1-01M Active GMP Recombinant Mouse Csf1 Protein, His-Tagged E.coli His
Mouse CSF1-40M Recombinant Mouse M-CSF Yeast N/A
Mouse Csf1-95M Recombinant Mouse Csf1 E.coli N/A
Mouse Csf1-178M Recombinant Mouse Csf1 protein, His/S-tagged E.coli His/S
Mouse Csf1-100M Recombinant Mouse Csf1 protein E.coli N/A 230
Mouse Csf1-699M Recombinant Mouse Csf1 protein, His-tagged E.coli His Lys33~Ser204
Mouse CSF1-001MCL Recombinant Mouse CSF1 cell lysate Human Cell N/A
Mouse Csf1-222C Active Recombinant Mouse Csf1 Protein CHO
Mouse Csf1-1283M Recombinant Mouse Csf1 Protein, His-tagged E.coli N-His Glu262-Leu432
Mouse Csf1-18M Active Recombinant Mouse Csf1 Protein (Lys33-Pro187), C-His tagged, Animal-free, Carrier-free E.coli C-His Lys33-Pro187
Mouse CSF1-41M Active Recombinant Mouse CSF1 Protein E.coli
Mouse Csf1-334C Active Recombinant Mouse Csf1 Protein (156 aa) E.coli 156
Mouse Csf1-041M Active Recombinant Mouse Csf1 Protein HEK293
Mouse Csf1-1107M Recombinant Mouse Csf1 Protein, His-tagged HEK293F N-His Lys33-Glu262
Mouse Csf1-1106M Recombinant Mouse Csf1 Protein, His-tagged HEK293F N-His Lys33-Glu262
Mouse Csf1-6753M Recombinant Mouse Csf1 Protein (Lys33-Glu262) Mammalian cells Tag Free Lys33-Glu262
Mouse Csf1-042M Active Recombinant Mouse Csf1 Protein E.coli
Mouse Csf1-2159M Recombinant Mouse Csf1 Protein, His-tagged E.coli N-His Lys33-Glu262
Mouse Csf1-043M Recombinant Mouse Csf1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Csf1-115MG Active GMP Recombinant Mouse Csf1 protein HEK293 DNA sequence encoding Mouse M-CSF(NP_031804.3) was expressed with His tag at the C-terminal.
Mouse Csf1-46M Recombinant Active Mouse CSF1 Protein, His-tagged(C-ter) E.coli His(C-ter)
Rat Csf1-12R Active Recombinant Rat Csf1 E.coli N/A
Rat Csf1-13R Active Recombinant Rat Csf1 HEK293 N/A
Rat Csf1-14R Active Recombinant Rat Csf1 CHO N/A
Rat Csf1-179R Recombinant Rat Csf1 protein, His/S-tagged E.coli His/S
Rat Csf1-15R Recombinant Rat Csf1 Human Cell N/A
Rat Csf1-2161R Recombinant Rat Csf1 Protein, His&GST-tagged E.coli N-His&GST Glu261-Leu427
Rat CSF1-42R Active Recombinant Rat CSF1 Protein E.coli
Rat Csf1-387RG Active GMP Recombinant Rat Csf1 protein HEK293 DNA sequence encoding Rat M-CSF(NP_076471.3) was expressed with His tag at the C-terminal.
Rat Csf1-221C Active Recombinant Rat Csf1 Protein CHO
Rat Csf1-333C Active Recombinant Rat Csf1 Protein (155 aa) E.coli 155
Rat Csf1-6845R Recombinant Rat Csf1 Protein (Gln33-Arg254) Mammalian cells Tag Free Gln33-Arg254
Bovine CSF1-4398B Recombinant Bovine CSF1 Protein Yeast N/A 223aa
Cynomolgus CSF1-340C Recombinant Cynomolgus CSF1 Protein, Fc-tagged HEK293 Fc Met1-Asn190
Cynomolgus/Rhesus CSF1-339C Active Recombinant Cynomolgus/Rhesus CSF1 protein(Met1-Asn190), His-tagged HEK293 C-His Met1-Asn190
Homo sapiens (Human) RFL21736HF Recombinant Full Length Human Granulocyte-Macrophage Colony-Stimulating Factor(Csf2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (18-144)
Human, Cynomolgus CSF1-565HB Active Recombinant Human/Cynomolgus CSF1 protein, His-tagged, Biotinylated HEK293 His
Mus musculus (Mouse) RFL36342MF Recombinant Full Length Mouse Macrophage Colony-Stimulating Factor 1(Csf1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (33-552)
Chicken CSF1-4112C Recombinant Chicken CSF1 Mammalian Cell His
Chicken CSF1-4393C Recombinant Chicken CSF1 Protein Yeast N/A 240aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CSF1 Related Articles
  • CSF1 Related Research Area

CSF1 involved in several pathways and played different roles in them. We selected most pathways CSF1 participated on our site, such as Cytokine-cytokine receptor interaction, Cytokines and Inflammatory Response, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL10RA;KDR;CXCL11;Pdgfa&Pdgfb;CTF1;TNFSF10;IL3;CSF3R;NGFR
Cytokines and Inflammatory ResponseCSF2;CSF1;CSF3
Hematopoietic cell lineageGM13305;CD34;ITGA6;ITGA3;Itgam&Itgb2;IL5;CSF3R;THPO;TNF
Integrins in angiogenesisCSF1R;CSF1;ANGPTL3;EDIL3;MFGE8
Osteoclast differentiationSIRPG;FOS;MAPK13;LILRB2;FOSB;FOSL2;PPP3R2;IFNAR1;MAPK10
PI3K-Akt signaling pathwayCSF1R;CSF1;LAMC3;CHAD;CSF3R;EFNA2;PIK3AP1;COMP;CSH2
Rap1 signaling pathwayCSF1;LOC608458;PFN4;RGS14;EFNA4;EFNA2
Ras signaling pathwayMET;FGF7;FIGF;PLD2;ANGPT1;KSR1;NRAS;VEGFB;PLA2G2F

CSF1 has several biochemical functions, for example, cytokine activity, growth factor activity, macrophage colony-stimulating factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSF1 itself. We selected most functions CSF1 had, and list some proteins which have the same functions with CSF1. You can find most of the proteins on our site.

Function Related Protein
cytokine activityCMTM8;BMP1;IL13;CMTM4;VEGFA;IFNA4;TNFSF13;IL9;IL32
growth factor activityGDF5;FGF12A;KITLG;GMFB;RABEP1;LACRT;LEFTY1;NRG3;NTF3
macrophage colony-stimulating factor receptor bindingSTAP1;IL34;CSF1
protein bindingCOX8A;RARG;RECK;POLR1A;DNAJB5;LPXN;NPHP4;CASP1;HMGA2
protein homodimerization activityNADK2;CD200;WRN;GABRR1;UGT1A9;ATPIF1B;DNTTIP1;SRR;PLOD1

CSF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSF1.

SGTA; FHL3; NOTCH2NL; adhC; MYC

Moffat, L; Rothwell, L; et al. Development and characterisation of monoclonal antibodies reactive with porcine CSF1R (CD115). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 47:123-128(2014).
Sauter, KA; Pridans, C; et al. Pleiotropic effects of extended blockade of CSF1R signaling in adult mice. JOURNAL OF LEUKOCYTE BIOLOGY 96:265-274(2014).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does CSF1 affect cancer progression? 09/20/2022

CSF1 is implicated in tumor-associated macrophages, influencing tumor growth, invasion, and the tumor microenvironment.

What are the potential side effects of CSF1 therapy? 07/11/2022

Side effects may include immune-related adverse events, inflammation, and alterations in white blood cell counts.

Can CSF1 therapy be combined with other treatments? 08/26/2020

Yes, there is ongoing research on combining CSF1-targeted therapies with other immunotherapies or conventional treatments to enhance efficacy.

What are the challenges in developing CSF1-based therapies? 09/26/2019

Challenges include maintaining the balance of immune responses, potential off-target effects, and variability in patient responses.

In what ways is CSF1 being researched for neurological disorders? 10/01/2018

Studies are exploring its role in neuroinflammation, neuroprotection, and potential therapeutic interventions for conditions like Alzheimer's disease.

Customer Reviews (3)

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Reviews
10/30/2017

    The CSF1 protein is renowned for its exceptional quality and reliability, making it an ideal choice to fulfill my experimental requirements.

    03/10/2017

      With its high purity and stability, this protein ensures dependable and accurate results, which are crucial for the success of my research endeavors.

      06/09/2016

        Whether it is for investigating cellular pathways, studying protein functions, or exploring signaling cascades, the CSF1 protein offers unparalleled versatility and performance.

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