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Ctse

  • Official Full Name

    cathepsin E

  • Overview

    The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.
  • Synonyms

    CTSE; cathepsin E; CATE; CATE_HUMAN; Cathepsin E form II; Erythrocyte membrane aspartic proteinase; OTTHUMP00000034345; OTTHUMP00000034346; slow-moving proteinase;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Assay Kits
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CTSE-724H Active Recombinant Human CTSE, His-tagged Mammalian cells His
Human CTSE-255H Recombinant Human CTSE, His-tagged HEK293 His
Human CTSE-26489TH Recombinant Human CTSE Wheat Germ N/A 379 amino acids
Human CTSE-2104H Recombinant Human CTSE Protein, GST-tagged Wheat Germ GST
Human CTSE-489H Recombinant Human cathepsin E, His-tagged E.coli His
Human CTSE-11685H Recombinant Human CTSE, GST-tagged E.coli GST 108-275a.a.
Human CTSE-5090H Recombinant Human CTSE, His-tagged E.coli His
Human CTSE-104HF Recombinant Full Length Human CTSE Protein In Vitro Cell Free System 379 amino acids
Human CTSE-1291H Recombinant Human CTSE Protein, His&GST-tagged E.coli N-His&GST Ser20-Pro349
Human CTSE-2753H Recombinant Human CTSE Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CTSE-1588H Recombinant Human CTSE Protein (Ser20-Pro396), C-His tagged Mammalian cells C-His Ser20-Pro396
Human CTSE-2343HF Recombinant Full Length Human CTSE Protein, GST-tagged In Vitro Cell Free System GST 396 amino acids
Human CTSE-2753H-B Recombinant Human CTSE Protein Pre-coupled Magnetic Beads HEK293
Mouse Ctse-912M Recombinant Mouse Ctse protein, His-tagged HEK293 His Met1-Pro397
Mouse Ctse-749M Recombinant Mouse Cathepsin E, His-tagged Mammalian cells His
Mouse CTSE-2190MCL Recombinant Mouse CTSE cell lysate Human Cell N/A
Mouse Ctse-2065M Recombinant Mouse Ctse Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ctse-5637M Recombinant Mouse Ctse Protein (Ser60-Pro397), C-His tagged Mammalian cells C-His Ser60-Pro397
Mouse Ctse-2065M-B Recombinant Mouse Ctse Protein Pre-coupled Magnetic Beads HEK293
Rat CTSE-1664R Recombinant Rat CTSE Protein Mammalian Cell His
Rat Ctse-1150R Recombinant Rat Ctse Protein, His-tagged HEK293 His
Rat CTSE-1323R-B Recombinant Rat CTSE Protein Pre-coupled Magnetic Beads HEK293
Rat CTSE-1323R Recombinant Rat CTSE Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Kit-2145 Cathepsin E Fluorometric Activity Assay Kit N/A
Kit-2154 Cathepsin E Inhibitor Screening Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Ctse Related Articles
  • Ctse Related Research Area

Ctse involved in several pathways and played different roles in them. We selected most pathways Ctse participated on our site, such as Adaptive Immune System, Immune System, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ctse were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemASB10;AP1S3A;CD160;CTSD;KIF2B;KLRB1A;CHUK;FBXO44;SIGLEC11
Immune SystemSIGIRR;DUSP3;TRIM38;SPSB2;DDOST;CFHL4;TAX1BP1B;KIF18A;RNF19B
LysosomeGLA;ARSA;CLTCB;TPP1;MFSD8;AP3M1;ATP6V0A2B;SLC11A2;ATP6V0B
MHC class II antigen presentationKLC3;KIF3C;ACTR1B;DYNC1LI2;MGC174857;DYNC1I1;CTSLL;CTSO;CTSC

Ctse has several biochemical functions, for example, aspartic-type endopeptidase activity, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Ctse itself. We selected most functions Ctse had, and list some proteins which have the same functions with Ctse. You can find most of the proteins on our site.

Function Related Protein
aspartic-type endopeptidase activityNAPSA;BACE2;PSEN2;DDI1;CTSE;PGA5;ANK2B;NRIP2;PGA
protein homodimerization activityTCF3B;PEX11A;HPS4;CORO1A;EXT1;ADD2;RAP1GAP;NETO2;C6orf108

Ctse has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ctse here. Most of them are supplied by our site. Hope this information will be useful for your research of Ctse.

BAG6; EMG1

Zhang, Q; Zhao, XZ; et al. Expression and purification of soluble human cystatin C in Escherichia coli with maltose-binding protein as a soluble partner. PROTEIN EXPRESSION AND PURIFICATION 104:14-19(2014).
Walker, E; Gopalakrishnan, R; et al. Microscopic Detection of Quenched Activity-Based Optical Imaging Probes Using an Antibody Detection System: Localizing Protease Activity. MOLECULAR IMAGING AND BIOLOGY 16:608-618(2014).
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