GC
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Official Full Name
group-specific component (vitamin D binding protein)
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Overview
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] -
Synonyms
GC; group-specific component (vitamin D binding protein); DBP; GRD3; VDBG; VDBP; DBP/GC; HEL-S-51; vitamin D-binding protein; VDB; gc-globulin; vitamin D-binding alpha-globulin; epididymis secretory protein Li 51;
- Recombinant Proteins
- Cell & Tissue Lysates
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Transfected Stable Cell Lines
- Chicken
- HHV-1(strain 17)
- HHV-1(strain KOS)
- HHV-2
- HSV-1
- HSV-2
- Human
- Mouse
- Rat
- RVFV
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human Plasma
- In Vitro Cell Free System
- In vitro E. coli expression system
- Insect Cell
- Mammalian Cell
- Mammalian cells
- NS0
- Wheat Germ
- Yeast
- C
- 6×His
- Myc
- DDK
- Flag
- GST
- His
- His (Fc)
- Avi
- His|GST
- His|T7
- KSI
- sumostar
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- GC Related Articles
GC involved in several pathways and played different roles in them. We selected most pathways GC participated on our site, such as Metabolism, Metabolism of lipids and lipoproteins, Metabolism of steroid hormones and vitamin D, which may be useful for your reference. Also, other proteins which involved in the same pathway with GC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism | CYP46A1;CYGB1;ARSF;NUDT3A;CYP3A7-CYP3AP1;ACOT10;KCNS3;SLC25A27;ALOX5AP |
| Metabolism of lipids and lipoproteins | ACOT13;DECR1;CDK19;ARSD;OSBP;APOC2;MED6;Agmo;SACM1LA |
| Metabolism of steroid hormones and vitamin D | AKR1B15;GC;STARD5;CYP27B1;CYP24A1;HSD17B11;PPP1R2;CYP2R1 |
| Vitamin D (calciferol) metabolism | |
| Vitamin D synthesis |
GC has several biochemical functions, for example, actin binding, calcidiol binding, vitamin D binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GC itself. We selected most functions GC had, and list some proteins which have the same functions with GC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | DIAPH1;DAG1;ANTXR2A;ACTR3B;HPCA;GIPC1;S100A4;GMFB;WASLA |
| calcidiol binding | |
| vitamin D binding | CALB1;S100G;VDRA;GC |
| vitamin transporter activity | GC;STRA6 |
GC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GC here. Most of them are supplied by our site. Hope this information will be useful for your research of GC.
ACTA1; p29991-pro_0000037941; CCND3; GRB2; SERF2; RIF1; CDC73; PIK3R3; d-mannose; PPP2R2A
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