SRGN
-
Official Full Name
serglycin
-
Overview
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. -
Synonyms
SRGN; serglycin; PRG, PRG1, proteoglycan 1, secretory granule; PPG; serglycin proteoglycan; Chondroitin sulfate proteoglycan core protein; Cytolytic granule proteoglycan core protein; FLJ12930; gp600; Hematopoetic proteoglycan core protein; Mastocytoma proteoglycan core protein; MGC9289; OTTHUMP00000019716; P.PG; PG19 core protein; Pgsg; Platelet proteoglycan core protein; platelet proteoglycan protein core; PRG; PRG1; PROTEOGLYCAN 1; proteoglycan 1, secretory granule; Proteoglycan 10K core protein; Proteoglycan peptide core protein; PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE; secretory granule proteoglycan 1; Secretory granule proteoglycan core protein; Sgc; SRGN_HUMAN; hematopoetic proteoglycan core peptide; secretory granule proteoglycan core peptide; secreto;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E. coli
- E.coli
- HEK293
- Human Cell
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Protein Conjugation
- Wheat Germ
- C
- His
- GST
- His (Fc)
- Avi
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | SRGN-6884H | Recombinant Human Serglycin, His-tagged | E.coli | His | 28-158aa | |
Human | SRGN-31460TH | Recombinant Human SRGN | Wheat Germ | N/A | 66 amino acids | |
Human | SRGN-31396TH | Recombinant Human SRGN, His-tagged | E.coli | His | 131 amino acids | |
Human | SRGN-31397TH | Recombinant Human SRGN | Wheat Germ | N/A | 158 amino acids | |
Human | SRGN-2952H | Recombinant Human SRGN, GST-tagged | E.coli | GST | 23-158aa | |
Human | SRGN-513H | Recombinant Human SRGN, His tagged | Human Cell | His | ||
Human | SRGN-1119HCL | Recombinant Human SRGN cell lysate | Human Cell | N/A | ||
Human | SRGN-2734H | Recombinant Human SRGN Protein, His-tagged | E.coli | N-His | Tyr28-Leu158 | |
Human | SRGN-2836H | Recombinant Human SRGN Protein, His-tagged, OVA Conjugated | Protein Conjugation | N-His | Asp119-Gly148 | |
Human | SRGN-5977H | Recombinant Human SRGN Protein (Gly27-Leu158), N-His tagged | Mammalian cells | N-His | Gly27-Leu158 | |
Human | SRGN-494HF | Recombinant Full Length Human SRGN Protein | In Vitro Cell Free System | 158 amino acids | ||
Human | SRGN-2624H | Recombinant Human SRGN protein(81-150 aa), C-His-tagged | E. coli | C-His | 81-150 aa | |
Mouse | SRGN-15982M | Recombinant Mouse SRGN Protein | Mammalian Cell | His | ||
Mouse | Srgn-8125M | Recombinant Mouse Srgn protein, His-tagged | E.coli | His | Ala28~Ile152 (Accession # P13609) | |
Mouse | SRGN-8716M | Recombinant Mouse SRGN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | SRGN-8716M-B | Recombinant Mouse SRGN Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | SRGN-5741R | Recombinant Rat SRGN Protein | Mammalian Cell | His | ||
Rat | SRGN-5400R-B | Recombinant Rat SRGN Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | Srgn-2104R | Recombinant Rat Srgn Protein, His&GST-tagged | E.coli | N-His&GST | Arg76-Ile179 | |
Rat | SRGN-5400R | Recombinant Rat SRGN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | SRGN-4464R | Recombinant Rhesus monkey SRGN Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | SRGN-4280R | Recombinant Rhesus Macaque SRGN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | SRGN-4280R-B | Recombinant Rhesus Macaque SRGN Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | SRGN-7672Z | Recombinant Zebrafish SRGN | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- SRGN Related Research Area
SRGN involved in several pathways and played different roles in them. We selected most pathways SRGN participated on our site, such as Hemostasis, Platelet activation, signaling and aggregation, Platelet degranulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRGN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Hemostasis | CEACAM1;ABHD6B;OSTN;ATP2B3A;DOK2;MFN1;DGKG;F9B;STXBP3 |
Platelet activation, signaling and aggregation | PDPN;SRGN;CLU;IGF2B;GAS6;MMRN1;C6orf25;STXBP3;G6b |
Platelet degranulation | HRG;CD9A;SRGN;TFA;MMRN1;CD9B;F13A1A.1;CAP1;SPARC |
Response to elevated platelet cytosolic Ca2+ | STXBP3A;BRPF3;PLEK;STXBP3;SERPINF2B;MMRN1;IGF2B;MMRN2A;WDR1 |
SRGN has several biochemical functions, for example, collagen binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRGN itself. We selected most functions SRGN had, and list some proteins which have the same functions with SRGN. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
collagen binding | DDR1;TGFBI;ITGA3;PAK1;GPR56;CTSB;PODN;ACHE;DDR2 |
protein binding | ZMAT4;HDHD3;NAA50;BLOC1S2;SEC23A;BTF3L4;HGS;C8orf4;WDHD1 |
SRGN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRGN here. Most of them are supplied by our site. Hope this information will be useful for your research of SRGN.
SGTA; UBQLN1; UBQLN1; GZMB; VCAN; MMP9; cabc1_provu; PRF1; caf1M; FHL3; q5nem9_fratt
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All SRGN Products
Required fields are marked with *
My Review for All SRGN Products
Required fields are marked with *