udp
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Overview
Uridine phosphorypase(UDP) catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is uridine:phosphate alpha-D-ribosyltransferase. Other names in common use include pyrimidine phosphorylase, UrdPase, UPH, and UPase. -
Synonyms
Udp;uridine phosphorylase;ECK3825;JW3808;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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E.coli | Udp-782E | Recombinant E.coli Uridine Phosphorylase, His-tagged | E.coli | His | ||
Salmonella typhimurium | CEZ91P | Active Recombinant Salmonella typhimurium udp | E.coli | N/A | ||
Satsuma mandarin | UDP-1285S | Recombinant Satsuma mandarin UDP protein, His&Myc-tagged | Insect Cell | His&Myc | 1-511aa |
- Involved Pathway
- Protein Function
- Interacting Protein
udp involved in several pathways and played different roles in them. We selected most pathways udp participated on our site, such as Metabolic pathways, Pyrimidine metabolism, pyrimidine ribonucleosides degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with udp were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Metabolic pathways | HAO2;HPRT1;LIPC;LIPT1;DOLK;ARG1;DNMT1;CSAD;AMT |
Pyrimidine metabolism | TYMP;POLR2A;NT5C1B-RDH14;UCK2A;TRR1;NME5;POLR2H;POLA2;NT5C2 |
pyrimidine ribonucleosides degradation | |
salvage pathways of pyrimidine ribonucleotides |
udp has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by udp itself. We selected most functions udp had, and list some proteins which have the same functions with udp. You can find most of the proteins on our site.
Function | Related Protein |
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udp has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with udp here. Most of them are supplied by our site. Hope this information will be useful for your research of udp.
- Q&As
- Reviews
Q&As (6)
Ask a questionThe activity of UDP protein can be regulated by chemical modifications such as phosphorylation, dephosphorylation, and methylation. In addition, its activity can be regulated through interactions with other proteins.
In cell signal transduction, UDP protein can be used as a second messenger molecule to transmit signals to downstream effector molecules and participate in cell proliferation, differentiation, migration and other processes.
Studies have shown that the expression level of UDP protein in some tumors is abnormally elevated, which may promote the occurrence and development of tumors; In other tumors, the expression level of UDP protein may be reduced, resulting in impaired DNA synthesis and abnormal cell proliferation.
In the immune system, UDP protein can be used as an immunomodulatory molecule to participate in the activation, differentiation, proliferation and other processes of immune cells.
The regulation of UDP protein on gene expression can be studied by regulating its expression level or its activity.
New anticancer drugs or other therapeutic drugs can be developed through computer-aided drug design and other technologies targeting the active or binding sites of UDP proteins.
Customer Reviews (3)
Write a reviewUDP has a high band strength in Western blot, which improves the signal-to-noise ratio of the experiment.
Methods such as ELISA or immunostaining work well.
This protein performed well by testing kinetic parameters such as enzymatic reaction rate, binding affinity, etc.
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