|Product Overview:||This product is a selective inhibitor of NR2B-containing NMDAR with the formula of C88H138N26O44.|
|Description:||Conantokin-G is aconopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-Gselectively inhibits NR2B containing N-methyl-D-aspartate receptors (NMDAR) with a high specificity. Thus, Conantokin-Ginhibits in a concentration-dependent manner the Ca2+influx leading to a neuroprotective effect against NMDA-induced excitotoxicity. Conantokin-G was shown to block NMDA-evoked currents in murine cortical neurons with an IC50 value of around 480 nM.|
|Form:||White lyophilized solid|
|Molecular Mass:||2264.23 Da|
|AA Sequence:||AA sequence: Gly-Glu-Gla-Gla-Leu-Gln-Gla-Asn-Gln-Gla-Leu-Ile-Arg-Gla-Lys-Ser-Asn-NH2|
|Purity:||> 95 %|
|Reconstitution:||Water or saline buffer|
Price does not include shipping and packaging costs.Request quote for final price.