"Conantokin-G" Related Products

Synthetic Conantokin-G

Cat.No.: TOXPP-588S
Product Overview: This product is a selective inhibitor of NR2B-containing NMDAR with the formula of C88H138N26O44.
Description: Conantokin-G is aconopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-Gselectively inhibits NR2B containing N-methyl-D-aspartate receptors (NMDAR) with a high specificity. Thus, Conantokin-Ginhibits in a concentration-dependent manner the Ca2+influx leading to a neuroprotective effect against NMDA-induced excitotoxicity. Conantokin-G was shown to block NMDA-evoked currents in murine cortical neurons with an IC50 value of around 480 nM.
Source: Synthetic
Species: Synthetic
Form: White lyophilized solid
Molecular Mass: 2264.23 Da
Protein length: 17
AA Sequence: AA sequence: Gly-Glu-Gla-Gla-Leu-Gln-Gla-Asn-Gln-Gla-Leu-Ile-Arg-Gla-Lys-Ser-Asn-NH2
Purity: > 95 %
Reconstitution: Water or saline buffer

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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