"ω-Conotoxin-GVIA" Related Products

Synthetic ω-Conotoxin-GVIA

Cat.No.: TOXPP-559S
Product Overview: This product is a selective blocker of Cav2.2 channel with the formula of C120H182N38O43S6.
Description: ω-conotoxin-GVIA (omega conotoxin GVIA) is a conotoxin that has been isolated from the venom of the cone Conus geographus. ω-conotoxin GVIA acts at presynaptic membranes. It binds and blocks specifically voltage-dependent N-type Ca2+channels Cav2.2 channel with an ED50 of 68pM.
Source: Synthetic
Species: Synthetic
Form: White lyophilized solid
Molecular Mass: 3036.05 Da
Protein length: 27
AA Sequence: AA sequence: H-Cys1-Lys-Ser-Hyp-Gly-Ser-Ser-Cys8-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys15-Cys16-Arg-Ser-Cys19-Asn-Hyp-Tyr-Thr-Lys-Arg-Cys26-Tyr-NH2
Disulfide Bonds: Cys1-Cys16; Cys8-Cys19; Cys15-Cys26
Purity: > 95 %
Reconstitution: Water or saline buffer

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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