"α-conotoxin-MI" Related Products

Synthetic α-conotoxin-MI

Cat.No.: TOXPP-571S
Product Overview: This product is a blocker of the α/δ site of the muscle-type nAChR with the formula of C58H88N22O17S4.
Description: α-conotoxin MI (alpha-conotoxin MI) is aconotoxin that has been isolated from the venom of the cone snail Conus magus. α-conotoxin MI is a competitive antagonist of the muscle-type nicotinic acetylcholine receptors (nAChR) such as α-conotoxin GIor d-Turbocurarine. It binds to the receptor with a Kd value ~0,94nM. α-conotoxin MI allows to distinguish between the two agonist sites as it binds 10,000-fold more tightly to the α/δ than to the α/γ site.
Source: Synthetic
Species: Synthetic
Form: White lyophilized solid
Molecular Mass: 1495.08 Da
Protein length: 14
AA Sequence: AA sequence: Gly-Arg-Cys3-Cys4-His-Pro-Ala-Cys8-Gly-Lys-Asn-Tyr-Ser-Cys14-NH2
Disulfide Bonds: Cys3-Cys8; Cys4-Cys14
Purity: > 97 %
Reconstitution: Water or saline buffer

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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