"ω-Conotoxin-MVIIA" Related Products

Synthetic ω-Conotoxin-MVIIA

Cat.No.: TOXPP-557S
Product Overview: This product is a potent blocker of Cav2.2 with the formula of C102H172N36O32S7.
Description: ω conotoxin MVIIA (omega conotoxin MVIIA) has been isolated from the venom of the cone Conus magus. Omega-conotoxinsact at presynaptic membranes, they bind and block voltage-sensitive calcium channels (VSCC). ω conotoxin MVIIA blocks N-type voltage-gated calcium channels (Cav2.2/CACNA1B). It blocks acute pain in patients who no longer obtain relief from opiate drugs. It is 100 to 1000 times more potent than morphine. This toxin blocks calcium channels and disables nerves that transmit pain signals.
Source: Synthetic
Species: Synthetic
Form: White lyophilized solid
Molecular Mass: 2639.18 Da
Protein length: 25
AA Sequence: AA sequence: Cys1-Lys-Gly-Lys-Gly-Ala-Lys-Cys8-Ser-Arg-Leu-Met-Tyr-Asp-Cys15-Cys16-Thr-Gly-Ser-Cys20-Arg-Ser-Gly-Lys-Cys25-NH2
Disulfide Bonds: Cys1-Cys16; Cys8-Cys20; Cys15-Cys25
Purity: > 97 %
Reconstitution: Water or saline buffer

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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