"ω-Conotoxin-MVIIC" Related Products

Synthetic ω-Conotoxin-MVIIC

Cat.No.: TOXPP-558S
Product Overview: This product is a blocker of P/Q and N-type Ca2+channels with the formula of C106H178N40O32S7.
Description: ω-conotoxin MVIIC (omega conotoxin MVIIC )is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIICis a blocker of P/Q (IC50=35 nM) and N-type calcium channels. It inhibits presynaptic Ca2+channels, including the Ca2+channels responsible for Ca2+uptake by rat brain synaptosomes, the P-type Ca2+channels in cerebellar Purkinje cells, and a significant fraction of ω-conotoxin GVIA-resistant currents in hippocampal CA1 neurons. ω-conotoxin MVIIC also presents an inhibition of ω-conotoxin GVIA-resistant depolarization-induced neurotransmitter release in cerebellar neurons of rats.
Source: Synthetic
Species: Synthetic
Form: White lyophilized solid
Molecular Mass: 2750.20 Da
Protein length: 26
AA Sequence: AA sequence: Cys1-Lys-Gly-Lys-Gly-Ala-Pro-Cys8-Arg-Lys-Thr-Met-Tyr-Asp-Cys15-Cys16-Ser-Gly-Ser-Cys20-Gly-Arg-Arg-Gly-Lys-Cys26-NH2
Disulfide Bonds: Cys1-Cys16; Cys8-Cys20; Cys15-Cys26
Purity: > 97 %
Reconstitution: Water or saline buffer

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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