"ρ-Da1a – AdTx1" Related Products

Synthetic ρ-Da1a – AdTx1

Cat.No.: TOXPP-585S
Product Overview: This product is a selective antagonist of the alpha(1A)-adrenoceptor with the formula of C310H481N87O100S8.
Description: AdTx1 (rho-Da1a – ρ-Da1a) is a 65 amino-acid peptide originally isolated from the venom of the green mamba, an African snake (Dendroaspis angusticep). AdTx1 is stabilized by four disulfide bridges and belongs to the family of the three-finger-fold peptide. AdTx1 has subnanomolar affinity (K(i)= 0.35 nM) and high specificity for the human alpha (1A)-adrenoceptor subtype and is 1000 times more potent on this subtype than on other adrenoceptor subtypes. AdTx1 is a potent relaxant of smooth muscles.
Source: synthetic
Species: synthetic
Form: White lyophilized solid
Molecular Mass: 7283.29 Da
Protein length: 65
AA Sequence: AA sequence: LTC3VTSKSIFGITTEDC17PDGQNLC24FKRRHYVVPKIYDSTRGC42AATC46PIPENYDSIHC57C58KTDKC63NE
Disulfide Bonds: Cys3-Cys24; Cys17-Cys42; Cys46-Cys57; Cys58-Cys63
Purity: > 98 %
Reconstitution: Water or saline buffer

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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