"HsTx1" Related Products

Synthetic HsTx1

Cat.No.: TOXPP-544S
Product Overview: This product is a selective blocker of Kv1.3 channel with the formula of C149H246N54O46S9.
Description: HsTx-1 is a member of the a-KTx6 family of scorpion toxins active on voltage-gated Kv1.3 channels (Kdclose to 10 pM).HsTx-1 is also very active on Kv1.1 channels (IC50 around 7 nM). It is however inactive on apamin-sensitive SK channels. It is one of the most potent toxins active on Kv1.3 channel.
Source: Synthetic
Species: Synthetic
Form: White lyophilized solid
Molecular Mass: 3819.87 Da
Protein length: 34
AA Sequence: AA sequence: Ala-Ser-Cys3-Arg-Thr-Pro-Lys-Asp-Cys9-Ala-Asp-Pro-Cys13-Arg-Lys-Glu-Thr-Gly-Cys19-Pro-Tyr-Gly-Lys-Cys24-Met-Asn-Arg-Lys-Cys29-Lys-Cys31-Asn-Arg-Cys34-NH2
Disulfide Bonds: Cys3-Cys24; Cys9-Cys29; Cys13-Cys31; Cys19-Cys34
Purity: > 95 %
Reconstitution: Water or saline buffer

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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