"Iberiotoxin" Related Products

Synthetic Iberiotoxin

Cat.No.: TOXPP-539S
Product Overview: This product is a blocker of high conductance Ca2+-activated K+channel with the formula of C179H274N50O55S7.
Description: Iberiotoxin (IbTx) is a toxin that was originally isolated from Buthus tamulusscorpion venom. Iberiotoxin inhibits selectively thehigh conductance Ca2+-activated K+channel (KCa1.1) at nanomolar concentrations (IC50~2 nM). This toxin does not affect other types of calcium-dependent or voltage-dependent K+channels. Iberiotoxin is a valuable tool to study specificallyMaxi-K channels.
Source: Synthetic
Species: Synthetic
Form: White lyophilized solid
Molecular Mass: 4230.8 Da
Protein length: 37
AA Sequence: AA sequence: pGlu-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-GIu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-GIn-OH
Disulfide Bonds: Cys7-Cys28; Cys13-Cys33; Cys17-Cys35
Purity: > 95 %
Reconstitution: Water or saline buffer
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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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