"Margatoxin" Related Products

Synthetic Margatoxin

Cat.No.: TOXPP-546S
Product Overview: This product is a Kv1.3 selective blocker with the formula of C178H286N52O50S7.
Description: Margatoxin (MgTx) is a component of the venom of Scorpio Centruroides margaritatus. Margatoxin preferentially inhibits voltage-dependent potassium channels Kv1.3 with an IC50 value around 50 pM (20 fold more potent thanCharybdotoxin) and irreversibly inhibits the proliferation responseof human T-cellsat 20 µM concentration.Margatoxinis known to be less potent on Kv1.3 expressed in Xenopus Oocytes (IC50around 1 nM). Margatoxinwas also described to be a potent inhibitor of human vascular smooth muscle cell migration with an IC50 of 85 pM.
Source: Synthetic
Species: Synthetic
Form: White lyophilized solid
Molecular Mass: 4179.03 Da
Protein length: 39
AA Sequence: AA sequence: Thr-Ile-Ile-Asn-Val-Lys-Cys7-Thr-Ser-Pro-Lys-Gln-Cys13-Leu-Pro-Pro-Cys17-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys29-Met-Asn-Gly-Lys-Cys34-Lys-Cys36-Tyr-Pro-His-OH
Disulfide Bonds: Cys7-Cys29; Cys13-Cys34; Cys17-Cys36
Purity: > 97 %
Reconstitution: Water or saline buffer
Products Types

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.