Active Recombinant Human CD38 protein, His/Avi-tagged, Biotinylated
Cat.No. : | CD38-051H |
Product Overview : | Biotinylated Recombinant Human CD38(Val43-Ile300) protein, fused to His/Avi tag at the C-terminus, was expressed in HEK293 cells . |
- Specification
- Gene Information
- Related Products
Description : | CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose (1). CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells (2, 3). Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells (4, 5). Our Avi-tag Biotinylated Recombinant Human CD38 features biotinylation at a single site contained within the Avi-tag, a unique 15 amino acid peptide. Protein orientation will be uniform when bound to streptavidin-coated surface due to the precise control of biotinylation and the rest of the protein is unchanged so there is no interference in the protein's bioactivity. |
Source : | HEK293 cells |
Species : | Human |
Tag : | His/Avi |
Predicted N Terminal : | Val43 |
Form : | Supplied as a 0.2 μm filtered solution in PBS. |
Bio-activity : | Measured by its ability to convert the substrate nicotinamide guanine dinucleotide (NGD+) to cyclic GDP-ribose. The specific activity is >1500 pmol/min/μg, as measured under the described conditions. Measured by its binding ability in a functional ELISA. When Human CD38 Antibody is immobilized at 1 µg/mL (100 µL/well), it binds to Biotinylated Recombinant Human CD38 His-tag Avi-tag with an ED50 of 1-6 ng/mL. |
Molecular Mass : | 40-52 kDa, under reducing conditions |
Protein length : | Val43-Ile300 |
Endotoxin : | <0.10 EU per 1 μg of the protein by the LAL method. |
Purity : | >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Applications : | Binding Activity, Enzyme Activity |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.6 months from date of receipt, -20 to -70 °C as supplied.3 months, -20 to -70 °C under sterile conditions after opening. |
Gene Name : | CD38 CD38 molecule [ Homo sapiens ] |
Official Symbol : | CD38 |
Synonyms : | CD38; CD38 molecule; CD38 antigen (p45); ADP-ribosyl cyclase 1; ADP ribosyl cyclase 1; NAD(+) nucleosidase; cADPr hydrolase 1; cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; T10; |
Gene ID : | 952 |
mRNA Refseq : | NM_001775 |
Protein Refseq : | NP_001766 |
MIM : | 107270 |
UniProt ID : | P28907 |
Products Types
◆ Lysates | ||
CD38-2639MCL | Recombinant Mouse CD38 cell lysate | +Inquiry |
CD38-1025RCL | Recombinant Rabbit CD38 cell lysate | +Inquiry |
CD38-1259RCL | Recombinant Rat CD38 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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