Active Recombinant Mouse Chemokine (C-X-C motif) Ligand 11 Cxcl11-386M

Active Recombinant Mouse Chemokine (C-X-C motif) Ligand 11

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Active Recombinant Mouse Chemokine (C-X-C motif) Ligand 11

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Cat.No. : Cxcl11-386M Optional Service: Optional requirements on this protein
Product Overview : Recombinantmouse Cxcl11 protein was expressed in E. coli. Phe22-Met100.
Description : Cxcl11 is a memberwithin the non-ELR CXC chemokine subgroup and has been designated Cxcl11.Cxcl11, together with MIG and IP10, constitute a subset of chemokines thatare ligands for CXCR3, a chemokine receptor that is primarily expressed onactivated Th1 cells and NK cells. The three chemokines were also reported to actas antagonists for CCR3, a chemokine receptor that is preferentiallyexpressed on activated Th2 cells.
Source : E. coli
Form : Lyophilized from a0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrierprotein.
N-terminal Sequence : Phe22
Molecular Weight : 9.1 kDa
Activity : Measured by itsability to chemoattract human CXCR3 transfected BaF3 mouse pro-B cells. TheED50 for this effect is typically 3-15 ng/mL.
Endotoxin Level : <1.0 EU per 1 μgof the protein by the LAL method.
Purity : >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 100μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to-70°C under sterile conditions after reconstitution.
PDB rendering based on 1rjt. :

Gene Name : Cxcl11chemokine (C-X-C motif) ligand 11 [ Mus musculus ]
Official Symbol : Cxcl11
Synonyms : Cxcl11; chemokine(C-X-C motif) ligand 11; Ip9; H174; Itac; b-R1; Cxc11; I-tac; Scyb11;Scyb9b; betaR1; C-X-C motif chemokine 11; small-inducible cytokine B11;interferon-inducible T-cell alpha chemoattractant; small-inducible cytokinesubfamily B (Cys-X-Cys), member 11; I-TAC
Gene ID : 56066
mRNA Refseq : NM_019494
Protein Refseq : NP_062367
UniProt ID : Q9JHH5
Chromosome Location : 5
Pathway : Chemokine signalingpathway; Cytokine-cytokine receptor interaction; Toll-like receptor signalingpathway
Function : chemokine activity;cytokine activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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