Active Recombinant Mouse Cxcl1 Protein
|Product Overview :||Purified recombinant protein of Mouse chemokine (C-X-C motif) ligand 1 (Cxcl1) without tag was expressed in E.coli.|
- Gene Information
- Related Products
|Description :||This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung.|
|Source :||E. coli|
|Bio-activity :||Determined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml.|
|Molecular Mass :||7.8 kDa|
|AA Sequence :||APIANELRCQCLQTMAGIHLKNIQS LKVLPSGPHCTQTEVIATLKNGREA CLDPEAPLVQKIVQKMLKGVPK|
|Endotoxin :||Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)|
|Purity :||>95%, as determined by SDS-PAGE and Coomassie blue staining|
|Stability :||Stable for at least 6 months from date of receipt under proper storage and handling conditions.|
|Storage :||Store at -80 centigrade.|
|Storage Buffer :||Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2|
|Reconstitution :||Resuspend the protein in the desired concentration in proper buffer.|
|Gene Name :||Cxcl1 chemokine (C-X-C motif) ligand 1 [ Mus musculus (house mouse) ]|
|Official Symbol :||Cxcl1|
|Synonyms :||Cxcl1; chemokine (C-X-C motif) ligand 1; KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1; growth-regulated alpha protein; C-X-C motif chemokine 1; GRO1 oncogene; KC/GR)-alpha; KC/GRO-alpha; alpha-chemokine; platelet-derived growth factor-inducible protein KC; secretory protein N51|
|Gene ID :||14825|
|mRNA Refseq :||NM_008176|
|Protein Refseq :||NP_032202|
|UniProt ID :||P12850|
|◆ Recombinant Protein|
|Cxcl1-53M||Active Recombinant Mouse CXCL1 Protein||+Inquiry|
|Cxcl1-032C||Active Recombinant Mouse Cxcl1 Protein (72 aa)||+Inquiry|
|CXCL1-389C||Active Recombinant Human CXCL1 Protein (73 aa)||+Inquiry|
|Cxcl1-187C||Active Recombinant Rat Cxcl1 Protein||+Inquiry|
|Cxcl1-011C||Active Recombinant Rat Cxcl1 Protein (72 aa)||+Inquiry|
|◆ Native Protein|
|CXCL1-27707TH||Native Human CXCL1||+Inquiry|
|CXCL1-425HCL||Recombinant Human CXCL1 cell lysate||+Inquiry|
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (7)Ask a question
Therapeutic strategies targeting CXCL1 aim to modulate its activity in diseases like cancer and chronic inflammation.
It mediates inflammation by promoting leukocyte migration and activation.
In cancer, CXCL1 can promote tumor growth, metastasis, and angiogenesis.
CXCL1 contributes to angiogenesis, supporting new blood vessel formation.
CXCL1 is a chemokine that attracts neutrophils to sites of infection or injury.
CXCL1 levels are elevated in conditions like cancer, inflammatory diseases, and infections.
CXCL1 expression is regulated by various stimuli, including cytokines and growth factors.
Customer Reviews (3)Write a review
Efficient delivery, great service. -
Product as described, perfect. -
Reliable for protein work. -
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