ADRB2 Total GPCR Internalization Assay Kit

• Cat.No.: Kit-2185
• Product Overview: Total GPCR Internalization cells are engineered to co-the Enzyme Acceptor (EA) tagged GPCR, and a ProLink (PK) tag localized to the endosomes. Activation of the GPCR-EA induces internalization of the receptor in PK-tagged endosomes, forcing complementation of the two β-galactosidase enzyme fragments (EA and PK). The resulting functional enzyme hydrolyzes substrate to generate a chemiluminescent signal. These cells have been modified to prevent long term propagation and expansion using a proprietary compound that has no apparent effect on assay performance.

Specification

• Storage: Short term (2 weeks): Store in vapor phase of liquid N2
• Size: 100 dp
  (1 x 96-well)/200 dp
  (2 x 96-well)/1000 dp
  (10 x 96-well)