As we know, exosomes are small vesicles secreted by cells. Therefore, exosomes have the characteristics of donor cells and have certain cell specificity. In a large number of studies on exosomes in cancer patients, it has been found that exosomes secreted by cancer cells have characteristic molecules that can be used to distinguish other exosomes, and can be used as molecular markers for cancer diagnosis. At present, the common molecular…
Month: May 2019
Overview of Formation and Function of Exosomes as well as The Important Role in The Occurrence and Deterioration of Cancer
In the early 1980s, researchers discovered exocytosis in normal cells or tumor cells cultured in vitro, and cells secreted vesicle structures with cell membrane characteristics in their culture medium. In 1983, Johnstone found that in vitro cultured sheep stromal erythrocytes excreted small vesicle structures containing transferrin receptors during maturation, they named the small vesicle structure released by the cell as an exosomes. Early detection of exocrine-secreting cells is mainly…