The Use of Activin/GDF Fusion Protein Is Expected to Treat Pulmonary Hypertension

Pulmonary hypertension (PAH) is an insidious disease. Its symptoms may start slowly, and even before the symptoms appear, extensive damage has caused the blockage of small arteries, resulting in increased blood pressure in the lungs. When the symptoms—the most obvious being shortness of breath—are severe enough for PAH patients to seek treatment and obtain a definite diagnosis, based on currently available treatments, the patient’s chance of survival within five years…

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Inhibition of the STING Protein Pathway Can Prevent Patients from Developing Graft-versus-host Disease

In a new study, researchers found that inhibiting the STING protein pathway can protect some patients from graft versus host disease (GVHD), among which, GVHD is the most serious complication of bone marrow (stem cell) transplantation. The relevant research results were published in the journal Science Translational Medicine. The title of the paper is “STING differentially regulates experimental GVHD mediated by CD8 versus CD4 T cell subsets”.   Dr. Levy…

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