Wang Lan’s research group of the Chinese Academy of Sciences Shanghai Institute of Nutrition and Health published the research achievement entitled “The cell non-autonomous function of ID1 promotes AML progression via ANGPTL7 from the microenvironment” online on Blood. This study reveals the key role of transcription regulatory factor ID1 in the bone marrow microenvironment in the initiation and progression of acute myeloid leukemia (AML), providing new ideas and strategies for…
acute myeloid leukemia
JCI: STAT3 Inhibitor May Provide New Hope for Leukemia Treatment
Myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) are malignant hematopoietic stem cell disorders, and abnormal stem cell populations in hematopoietic stem and progenitor cells can cause disease. Traditional treatments to date can not completely eliminate these abnormal hematopoietic stem cells associated with the disease. Recently, researchers from the Albert Einstein College of Medicine have discovered a prognosis molecule that predicts both MDS and AML. Furthermore, an antisense oligonucleotide…