New Co-stimulatory Signal Enables CAR-T to Show Its Potential in the Treatment of Solid Tumors

Chimeric antigen receptor (CAR) expressing T cells (CAR-T therapy) is one of the major breakthroughs in the field of cancer treatment in recent years, and has achieved excellent results in the treatment of blood cancer. CAR is like a “GPS navigation system” for T cells, so that T cells can quickly locate tumor cells that are good at camouflage, so as to find and kill them. So far, two CAR-T…

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Immunity: Why Can’t HIV Be Cured? Scientists Find the Key Mechanism!

Due to the rapid development of antiretroviral therapy (ART), HIV patients can live longer than before. But even if it is a very effective long-term ART, the HIV virus remains stubbornly incurable, so patients need medication for life. Scientists have been convinced that this is because the HIV virus has created a stubborn virus-infected cell nest that allows HIV to survive indefinitely. A recent study done by researchers at Brigham…

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